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DNA studies: a novel structural transition, relaxation of secondary structure by TOPO I, and resolution of a PCR problem
(2006)Both theory and experiments were employed previously to investigate the effects of small neutral osmolytes on the twist energy parameter ( ET) and average intrinsic twist (l 0) of p30delta DNA (4932 bp). The results for ... -
DNA tumor virus oncogenes antagonize the cGAS-STING DNA sensing pathway
A key aspect of antiviral immunity is the induction of type I interferons (IFN) to mediate the effective clearance of a viral infection. Cyclic GMP-AMP synthase (cGAS) detects intracellular DNA and signals through the ... -
DNA-binding independent mechanism of TATA-binding protein at TATA-less genes
(2013-11-14)The core promoter is defined as the minimal sequence of DNA surrounding the transcription start site that is required for transcription of mRNA genes by the eukaryotic RNA Polymerase II (Pol II). Multiple core promoter ... -
Do all of these meetings matter? Three essays concerning the impacts of collaborative watershed governance.
My dissertation presents three related projects. In each project, I make a novel contribution to the understanding of collaborative environmental governance in theory and practice. I focus on a common application of ... -
Do Balanus glandula consume brine shrimp cysts?
(Friday Harbor Labs, 2011-05)The barnacle, Balanus glandula, is a good experimental organism for studying the impacts of both temperature and flow rate on filter feeding efficiency. Such knowledge has important implications for understanding the ... -
Do caregiving-related stress and emotion regulation impact treatment adherence to a caregiver-mediated intervention for toddlers at risk for ASD?
Caregivers of toddlers with autism spectrum disorder (ASD) experience increased levels of caregiving-related stress, which can impede gains their toddlers make from participating in interventions. Treatment adherence (i.e., ... -
Do Commissions Cause Investment Adviser Misconduct?
Sales commissions may present a conflict of interest that allows investment advisers to obtain rents from uninformed clients. Alternatively, commissions might be a contracting solution to motivate information provision. ... -
Do Complete Streets Offer Cyclists High Levels of Service? Applying David Harkey’s Bicycle Compatibility Index to Seattle and Copenhagen’s Complete Street Networks
Cities like Seattle are looking to increase active transportation trips like cycling over automotive trips to meet sustainability and equity goals. Seattle works to create “complete streets,” roads that provide infrastructure ... -
Do drinking consequences predict sexual revictimization in a college sample of binge-drinking women?
Sexual victimization is prevalent on college campuses in the US. A proportion of women experience multiple sexual assaults, and sexual assault risk in college is heightened among those with prior victimization histories. ... -
Do freshwater growth opportunities and migration barriers limit recovery of imperiled anadromous Oncorhynchus mykiss populations?
Steelhead (Oncorhynchus mykiss) populations in the Puget Sound Distinct Population Segment are far below their historic abundance and are currently listed as Threatened under the Endangered Species Act. Despite the declines ... -
Do hospital performance rankings sufficiently account for underlying patient risk? The value of information in outcomes-based risk adjustment
(2013-11-14)Objective: To determine the optimal amount of information that should be included in a risk adjustment model as it pertains to health care performance based financing. Data Sources: Health Care Cost and Utilization Project ... -
Do I Need a PHD to Vote: A Qualitative and Quantitative Study
(2022)Throughout history, U.S ballots have been designed by the most educated and sophisticated. Research shows that even the most educated individuals do not possess the tools and knowledge necessary to understand many ballots. ... -
Do Infants Generalize Other People's Emotional Dispositions Across Contexts?
This study explored 15-month-old infants' ability to attribute emotional dispositions to others. Infants (N = 72) participated in three Emotional Eavesdropping trials in which they saw an Experimenter demonstrate an ... -
Do It Off Broadway: Exploring the Politics of Diversity and Inclusion in Museums Through Risk, Advocacy, and Queer Experience
What does it mean for museums to be diverse and inclusive? Does inclusion just mean representation, or does it also require a degree of institutional allyship and pursuit of change? This research study seeks to explore, ... -
Do maternal cells trigger or perpetuate autoimmune diseases in children?
(2007)The placental barrier is not the impenetrable wall that it was once presumed to be. During pregnancy, fetal cells pass into the mother, where they persist for decades after the pregnancy, leading to fetal microchimerism ... -
Do Mindfulness and/or Thought Suppression Mediate Treatment Effects on Cardiac Vagal Control in Substance Abusers treated with Mindfulness-Based Relapse Prevention, Relapse Prevention or Treatment as Usual?
(2014-04-30)Thought suppression, or the effort to reduce or stop thinking about a particular thought (i.e., target thought of anticipated pleasant sensations associated with drug), is involved with many effective therapeutic strategies ... -
Do neural measures of executive function account for income differences in preschool children's effortful control?
(2014-02-24)This study examined whether differences in neural processes of executive attention and inhibitory control accounted for income differences observed in performance on behavioral effortful control tasks. We aimed to clarify ... -
Do Pacific salmon hatchery programs work for their intended purpose?
Pacific salmon hatchery programs are used as a tool to increase the abundance, productivity, or probability of persistence of populations. Today, they are used throughout the North Pacific Rim. On the west coast of the ... -
Do perceptual subgroups exist in ataxic dysarthria?
When the cerebellar circuit is damaged, the resulting speech disturbance is known as ataxic dysarthria. Features of this disorder include irregular articulatory breakdowns, distorted vowels, excess and equal stress, prolonged ... -
Do screen time policies matter? The association between the presence of screen time policies in child care facilities and child care provider knowledge, provider advocacy and facility practices.
(2013-11-14)Background: Childhood obesity affects millions of children in the United States; the estimated prevalence of obesity among two to five year olds has doubled between 1980 and 2008. The American Academy of Pediatrics (AAP) ...