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Browsing by Subject "Molecular Sequence Data"
Now showing items 1-11 of 11
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Cloning and characterization of the mouse interleukin enhancer binding factor 3 (Ilf3) homolog in a screen for RNA binding proteins
(Springer-Verlag, 1999-05)In a screen for RNA-binding proteins expressed during murine spermatogenesis, we have identified a cDNA that encodes a protein of 911 amino acids that contains two copies of the double-stranded RNA-binding ... -
Cloning and distribution of galanin-like peptide mRNA in the hypothalamus and pituitary of the macaque
(Endocrine Society, 2002-03)Galanin-like peptide (GALP) is a newly discovered hypothalamic neuropeptide, which is regulated by leptin and implicated in the regulation of GnRH secretion in the rodent. We searched the human genome ... -
Germ cell defects and hematopoietic hypersensitivity to gamma-interferon in mice with a targeted disruption of the Fanconi anemia C gene
(American Society of Hematology, 1996-07-01)Fanconi anemia (FA) is an autosomal recessive chromosome instability syndrome characterized by progressive bone marrow (BM) failure, skeletal defects, and increased susceptibility to malignancy. FA cells are ... -
Germ cell-specific proteins interact with the 3' untranslated regions of Prm-1 and Prm-2 mRNA
(Elsevier, 1994-12)The testis-specific mouse protamine genes (Prm-1 and Prm-2) are transcribed in haploid round spermatids, their mRNAs stored as cytoplasmic ribonucleoprotein particles and translated about 1 week later in ... -
Identification of ZFR, an ancient and highly conserved murine chromosome-associated zinc finger protein
(Elsevier, 1999-03-04)In a screen for RNA binding proteins expressed during murine spermatogenesis, we cloned a novel, ancient zinc finger protein possessing a region common to a small class of RNA binding proteins. Zfr (zinc ... -
Mechanisms involved in the homologous down-regulation of transcription of the follicle-stimulating hormone receptor gene in Sertoli cells
(Elsevier, 2001-02-28)The action of follicle-stimulating hormone (FSH) in spermatogenesis is regulated at a fundamental level by controlling the number of competent receptors present at the surface of Sertoli cells. By controlling ... -
MSY2 and MSY4 bind a conserved sequence in the 3' untranslated region of protamine 1 mRNA in vitro and in vivo
(American Society for Microbiology, 2001-10)Y-box proteins are major constituents of ribonucleoprotein particles (RNPs) which contain translationally silent mRNAs in gametic cells. We have recently shown that a sequence-specific RNA binding activity ... -
Post-transcriptional control of gene expression during spermatogenesis
(Elsevier, 1998-08)The synthesis and storage of mRNAs prior to their translation is a necessity during spermatogenesis as global transcription ceases several days prior to the completion of spermatid differentiation. ... -
A sequence-specific RNA binding complex expressed in murine germ cells contains MSY2 and MSY4
(Elsevier, 2000-05)The protamine mRNAs are stored for up to 8 days as translationally repressed ribonucleoprotein particles during murine spermatogenesis. Translational repression of the protamine 1, Prm1, mRNA is controlled ... -
Spnr, a murine RNA-binding protein that is localized to cytoplasmic microtubules
(Rockefeller University Press, 1995-05)Previous studies in transgenic mice have established the importance of the 3' untranslated region (UTR) of the spermatid-specific protamine-1 (Prm-1) mRNA in its translational control during male germ cell ... -
A testis cytoplasmic RNA-binding protein that has the properties of a translational repressor
(American Society for Microbiology, 1996-06)Translation of the mouse protamine 1 (Prm-1) mRNA is repressed for several days during male germ cell differentiation. With the hope of cloning genes that regulate the translational repression of Prm-1, we ...