Now showing items 1-4 of 4

    • Adrenocortical responsiveness to infusions of physiological doses of ACTH is not altered in posttraumatic stress disorder 

      Radant, Allen D.; Dobie, Dorcas J.; Peskind, Elaine R.; Murburg, M. Michele; Petrie, Eric C.; Kanter, Evan D.; Raskind, Murray A.; Wilkinson, Charles W. (Frontiers in Behavioral Neuroscience, 2009-10-30)
      Early studies of posttraumatic stress disorder (PTSD) reported that abnormal function of the hypothalamic–pituitary–adrenocortical (HPA) system was associated with the disorder. However, subsequent studies attempting to ...
    • Glucocorticoid Induction of the Glaucoma Gene MYOC in Human and Monkey Trabecular Meshwork Cells and Tissues 

      Clark, Abbot F.; Steely, Thomas; Dickerson Jr., Jaime E.; English-Wright, Sherry; Stropki, Karen; McCartney, Mitchell D.; Jaconson, Nasreen; Shepard, Allan R.; Clark, John I.; Matsushima, Hiroyuki; Peskind, Elaine R.; Leverenz, James B.; Wilkinson, Charles W.; Swiderski, Ruth E.; Fingert, John H.; Sheffield, Val C.; Stone, Edwin M. (Investigative Ophthalmology & Visual Science,, 2001-07)
      PURPOSE. To examine the intracellular and extracellular expression of myocilin in the human and primate trabecular meshwork (TM) in the presence and absence of glucocorticoids. METHODS. Myocilin expression was examined ...
    • High prevalence of chronic pituitary and target-organ hormone abnormalities after blast-related mild traumatic brain injury 

      Wilkinson, Charles W.; Pagulayan, Kathleen F.; Petrie, Eric C.; Mayer, Cynthia L.; Colasurdo, Elizabeth A.; Shofer, Jane B.; Hart, Kim L.; Hoff, David; Tarabochia, Matthew A.; Peskind, Elaine R. (Frontiers in Neurology, 2012-02-07)
      Studies of traumatic brain injury from all causes have found evidence of chronic hypopituitarism, defined by deficient production of one or more pituitary hormones at least 1 year after injury, in 25–50% ofcases. Most ...
    • Human Glucocorticoid Feedback Inhibition Is Reduced in Older Individuals: Evening Study 

      Wilkinson, Charles W.; Petrie, Eric C.; Murray, Sharon R.; Colasudro, Elizabeth A.; Raskind, Murray R.; Peskind, Elaine R. (The Journal of Clinical Endocrinology & Metabolism, 2001)
      We have previously shown that when tested in the morning, older men and women, pretreated with metyrapone to block endogenous cortisol synthesis, exhibit delayed suppression of plasma ACTH in response to cortisol infusion. ...