The system be down for regular maintenance on April 3rd, 2024 from 8:00-10:00am.
Browsing Dissertations and Theses by Subject "Calcineurin inhibitor; Cytochrome P450 3A5; Liver transplant; Nephrotoxicity; P-glycoprotein; Pharmacogenetics"
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Pharmacogenetic determinants of calcineurin inhibitor associated nephrotoxicity in liver transplant patients
(2013-11-14)The use of calcineurin inhibitors (tacrolimus and cyclosporine) has become standard of care in post-transplant immunosuppression. While these medications have greatly reduced organ rejection, they can cause nephrotoxicity ...