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Fine-tuning Engineered Gene Regulatory Networks Expressed in Escherichia coli using Hypervariable Simple Sequence Repeats
(2012-01-01)
Synthetic biology aims to borrow from the vast diversity of living systems shaped by evolutionary processes to create synthetic biological systems with comparable functional complexity to natural systems that meet pressing needs in health, energy, and the environ- ment. Construction of these systems is both aided by the ...
Adaptive Wireless Power for Ventricular Assist Devices
Every device needs power to function. Whether that device is a cell-phone, laptop, wearable device, or even a robot, if the power source dies then the device is unusable until charged up again. In our world today, this is something we are all too familiar with: the battery dies and the device is off until it is physically ...
Valuing Distributed Energy Resources
Due to their small scale, it is often difficult for Distributed Energy Resources (DERs) to compete with large centralized resources when their value is based purely on the cost of energy and capacity. In order for the true value of DERs to be realized, it is important that these resources be applied and compensated for a ...
Engineering Probes and Circuits for Detecting Single Nucleotide Variations in DNA and RNA
Even single nucleotide changes in nucleic acid sequence can result in drastic phenotype differences with significant health impact, such as driver mutations for cancer or antibiotics resistance in pathogens. However, reliable detection and quantitation of single nucleotide variants (SNVs) is challenging when the SNV is at low ...
Fast and Broadband Signal Integrity Analysis of Multiple Vias in Heterogeneous 3D IC and Die-Level Packaging by Using Generalized Foldy-Lax Scattering Method
This dissertation proposal is concerned with the use of fast and broadband full-wave electromagnetic methods for modeling high speed interconnects (e.g, vertical vias and horizontal traces) and passive components (e.g, decoupling capacitors) for structures of PCB and packages, in 3D IC, Die-level packaging and SIW based ...
Multiscale Modeling of Defect Generation and Diffusion in Semiconductor Materials
(2013-02-25)
As semiconductor device technology continues to evolve, great challenges arise in many areas. With the continuous shrinkage of the design window, a better understanding of the detailed physical processes that occur during fabrication is required. This dissertation utilizes the multiscale modeling approach to investigate such ...
Using Component Isolation to Increase Trust in Mobile Devices
Mobile phones pervade virtually every realm of societal interactions ranging from the obvious, communications and mobile payments, to the less obvious use of health monitoring. They also vary in complexity and cost with various offerings including smart, feature or basic phones. But these ubiquitous devices come with security ...
Dynamic Object Tracking and 3-D Visualization from Big Visual Data
We propose an automatic system which dynamically tracks video objects (human and vehicle) and create their 3-D visualization from big visual data. Big visual data implies that all videos are collected from either static or mobile surveillance cameras. Our goal is to track a video object within such a surveillance camera ...
A Platform for Microbial Evolution and Characterization
In this document we describe a novel platform for the engineered evolution of microbes. Our platform consists of three major components, which we discuss in subsequent chapters. Technology: We have developed a novel continuous culture device called the Flexostat. The Flexostat is a flexible, programmable, eight chamber, ...
Quality-Driven Cross Layer Design of Video Transmissions over MIMO Systems
Mobile data traffic has been exponentially increasing during the past years. With the prevalence of video-enabled mobile devices such as smart phones, more than half of the total mobile data traffics are attributed to mobile video traffics. Since wireless resource is limited and video-related applications are bandwidth-consuming, ...