Browsing Environmental health by Title
Now showing items 79-98 of 298
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Dairy Worker, Cow and Environmental Staphylococcus Presence on Washington State Dairy Farms
The “One Health” paradigm embraces the importance of interdisciplinary collaboration between multiple fields of study for a more comprehensive approach to the complex issues of interconnected human, animal and environmental ... -
Dermal absorption of benzo[a]pyrene from soil: Assessment of flux and application to risk assessment of contaminated sites
Soil cleanup standards and assessment of human health risks at contaminated sites are based in part on predicted human exposure to soil contaminants, including from direct skin contact. Available investigations of dermal ... -
Determinants of Depression and Anxiety in U.S. Mariners during the COVID-19 Pandemic
Objective: This study characterizes determinants of depression and anxiety among U.S. Mariners during the COVID-19 pandemic and identifies areas for intervention on these outcomes.Methods: We developed a cross-sectional ... -
Determining how Long Truck Driver Whole Body Vibration Exposure Data has to be collected to Accurate Estimate Actual Daily Exposures
Introduction: Exposure to Whole body Vibration (WBV) has been associated with increased prevalence of low back pain in occupational settings. Not only does exposure to WBV have a high personal cost for worker’s who experience ... -
Development of a Liver-Kidney Dual Organ Microphysiological System for Predicting Organ-Organ Interactions in the Toxicity of Xenobiotics: Aristolochic Acid Nephrotoxicity as a proof of Principle
The liver is the principal organ responsible for drug and xenobiotics metabolism, including inactivation or bioactivation. To improve the predictability of drug safety and efficacy in clinical development, and to facilitate ... -
Development of an LC-MS/MS Method for the Characterization of Halogenated Furanones
Halogenated furanones are chlorine disinfection by-products (DBPs) that have been shown to be direct acting mutagens and are considered potential human carcinogens. These high priority DBPs are among the by-products to be ... -
Development of Environmental Surveillance Methods for the Detection of Salmonella enterica serovar Typhi in Wastewater
Typhoid fever continues to be a leading cause of global morbidity and mortality, especially in developing countries with limited access to safe drinking water and adequate sanitation. Environmental surveillance – the process ... -
DEVELOPMENTAL EXPOSURE TO DIESEL EXHAUST CAUSES AUTISM-LIKE BEHAVIORAL, MOLECULAR, AND CORTICAL STRUCTURAL ALTERATIONS.
Escalating prevalence of autism spectrum disorders (ASD) in recent decades has triggered increasing efforts in understanding the role played by environmental risk factors as a way to address this widespread public health ... -
Developmental neurotoxicity of diesel exhaust in a Gclm heterozygous mouse model
The 2018 Environmental Performance Index (EPI) named air pollution as the number one environmental threat to public health. Traffic-related air pollution (TRAP) is a sizable contributor to global air pollution, and diesel ... -
Developmental toxicity of alkylating agents in differentiating cell cultures
(1996)Alkylating agents are well known carcinogens and teratogens. Highest exposures occur in occupational settings, although other lifestyle factors also contribute to exposure. The four alkylating agents used in this study ... -
Diesel Exhaust Exposure Induces Microglial Activation, Suppresses Adult Neurogenesis, and Increases Levels of Neurodegenerative Markers
Diesel exhaust (DE) is a major contributor to air pollution globally. Fine and ultrafine particulate matter make up a large portion of its components. For some time, exposure to high levels of traffic related particulate ... -
Dietary Phthalate Exposure in Pregnant Women
(2013-07-25)Background Phthalates are a family of synthetic chemicals with use in a variety of industrial and consumer products. Due to their ubiquity in the environment, exposures are widespread in the U.S. population. Animal studies ... -
Differential response and susceptibility to oxidative stress in mouse lung fibroblasts heterozygous for phospholipid hydroperoxide glutathione peroxidase (GPx4)
(2006)Phospholipid hydroperoxide glutathione peroxidase (GPx4) is a member of the family of selenium dependent enzymes that catalyze the reduction of cell membrane-bound phospholipid hydroperoxides in situ and thus, protects ... -
Differential Susceptibility to Engineered Nanomaterial Induced Lung Inflammation and Toxicity
Nanotechnology is a global industry producing a large variety of engineered nanomaterials (ENMs) for use in virtually every industry sector. Quantum dots (QDs) are ENMs with attractive semiconductor and fluorescent properties ... -
Differential Susceptibility to Quantum Dot Induced Lung Inflammation: A Systems Genetics Approach
(2013-02-25)University of Washington Abstract Differential Susceptibility to Quantum Dot Induced Lung Inflammation: A Systems Genetics Approach David K Scoville Chair of Supervisory Committee: Professor Terrance J Kavanagh Department ... -
Dynamic In Vitro Models for Reproductive and Developmental Toxicology
As in vitro models play an increasingly important role in evaluation of potential developmental and reproductive toxicants, it is essential that we define how well these models can capture developmental stages and processes ... -
Education, English Proficiency, and Health as Predictors of Employment among Filipino Migrants and Non-migrants
Immigrants face a number of unique challenges when migrating to the United States. One of the most important concerns is securing employment. For decades, Human Capital Theory has been the prevailing framework supporting ... -
Effects of Chlorpyrifos Exposure on Proliferation and Differentiation in Human Neural Progenitor Cells
(2013-07-25)An in vitro human neural progenitor cell (hNPCs) model was established to study adverse effects of the organophosphate pesticide chlorpyrifos (CP) during neuronal proliferation and differentiation. CP is of interest given ... -
Effects of Common E-Cigarette Compounds on Immortalized Mouse Hepatocytes and Glutathione as a Potential Modulator of Susceptibility
In 2018, 3.2% of adults reported currently using an e-cigarette (vaping) at least once in a 30-day period1. 20.8% and 4.9% of high school and middle school students, respectively, also reported using e-cigarettes during ... -
Effects of Diazinon and Diazoxon on Astrocyte-Neuronal Interactions: Inhibition of Neurite Outgrowth by Mechanisms of Oxidative Stress
(2013-11-14)Organophosphorus insecticides (OPs) are among the most widely-used class of insecticides in the world. Concern for the developmental neurotoxic potential of OPs has increased in recent years due to mounting in vitro, in ...