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Browsing by Subject "Gene Expression Regulation"
Now showing items 1-11 of 11
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Activation-dependent regulation of galanin gene expression in gonadotropin-releasing hormone neurons in the female rat [see comments]
(Endocrine Society, 1994-05)In rats, galanin is colocalized in GnRH neurons, and galanin mRNA in GnRH neurons is increased coincidentally with the preovulatory gonadotropin surge. Whether the induction of galanin mRNA in GnRH neurons ... -
Induction of galanin gene expression in gonadotropin-releasing hormone neurons with puberty in the rat
(Endocrine Society, 1994-10)The onset of puberty reflects the developmental activation of GnRH neurons whose secretory activity awakens the reproductive axis; however, the cellular mechanisms involved in this activational process remain ... -
Proopiomelanocortin neurons are direct targets for leptin in the hypothalamus
(Endocrine Society, 1997-10)Leptin is a protein product of the obese (ob) gene, which is secreted by adipocytes and functions as a satiety factor to regulate food intake. The expression of the leptin receptor in several hypothalamic ... -
Pubertal changes in gonadotropin-releasing hormone and proopiomelanocortin gene expression in the brain of the male rat
(Endocrine Society, 1989-04)Pubertal development in mammals is in part attributable to a brain-dependent process, whereby increased pulsatile GnRH secretion leads to the awakening of the entire reproductive system. However, the brain ... -
Regulation of galanin gene expression in gonadotropin-releasing hormone neurons during the estrous cycle of the rat
(Endocrine Society, 1993-04)Galanin is colocalized with GnRH in neurons of the hypothalamus and basal forebrain of female rats, and this neuropeptide may play a role in the generation of the midcycle surge of gonadotropin secretion. We ... -
Regulation of gonadotropin-releasing hormone (GnRH) and galanin gene expression in GnRH neurons during lactation in the rat [published erratum appears in Endocrinology 1994 Jan;134(1):498]
(Endocrine Society, 1993-09)Galanin is colocalized with GnRH, and its expression in these neurons is enhanced at proestrus, a time of activation of GnRH neurons. We tested the hypothesis that the expression of both the GnRH and galanin ... -
Regulation of somatostatin and growth hormone-releasing hormone gene expression in the rat brain
(Elsevier, 1990-09)We have studied the regulation of somatostatin (SS) and growth hormone-releasing hormone (GHRH) gene expression in the brain of the laboratory rat. We report that hypophysectomy in the adult male reduces SS ... -
Separate elements in the 3' untranslated region of the mouse protamine 1 mRNA regulate translational repression and activation during murine spermatogenesis
(Elsevier, 1997-11)The mouse protamine mRNAs, Prm-1 and Prm-2, are translationally repressed for several days during male germ cell differentiation. The translational delay of mouse Prm-1 mRNA has previously been shown to be ... -
Sexual dimorphism and testosterone-dependent regulation of somatostatin gene expression in the periventricular nucleus of the rat brain
(Endocrine Society, 1989-07)Gender differences in hypothalamic somatostatin (SS) secretion may account in part for the sexually dimorphic patterns of GH secretion in rats. Since males have lower baseline serum GH levels than females, ... -
Sexual dimorphism of growth hormone-releasing hormone and somatostatin gene expression in the hypothalamus of the rat during development
(Endocrine Society, 1991-05)The secretory pattern of GH secretion is markedly sexually dimorphic in the adult rat. The patterning of GH secretion is determined by the coordinated activity of somatostatin (SS)- and GH-releasing hormone ... -
Translational repression by MSY4 inhibits spermatid differentiation in mice
(Company Of Biologists Limited, 2002-08)In developing male germ cells, newly synthesized protamine mRNAs are stored for up to 7 days before translational activation. Translational repression of protamine 1 (Prm1) mRNA requires sequences present in ...