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Ovarian follicular concentrations of activin, follistatin, inhibin, insulin-like growth factor I (IGF-I), IGF-II, IGF-binding protein-2 (IGFBP-2), IGFBP-3, and vascular endothelial growth factor in spontaneous menstrual cycles of normal women of advanced reproductive age
(Endocrine Society, 2000-12)
Previous studies indicate that the menstrual cycles of older reproductive
age women are characterized by a selective elevation of FSH associated
with early development and ovulation of a dominant follicle. Several
intraovarian hormones and growth factors have been identified that appear
to serve ...
Age-related analysis of inhibin A, inhibin B, and activin a relative to the intercycle monotropic follicle-stimulating hormone rise in normal ovulatory women
(Endocrine Society, 2004-06)
Previous studies have reported that the monotropic rise in FSH in older
women is associated with decreased inhibin B and/or A levels and increased
levels of activin A. Whereas most investigators have found decreased
follicular-phase inhibin B, the roles of inhibin A and activin A as
modulators of ...
Reproductive ageing and ovarian function: is the early follicular phase FSH rise necessary to maintain adequate secretory function in older ovulatory women?
(Oxford University Press, 2005-01)
BACKGROUND: Serum FSH elevations and decreases in inhibin B have been
consistently demonstrated in the early follicular phase of cycles in women
of advanced reproductive age. However, secretory products of the dominant
follicle (estradiol and inhibin A) in the serum of older ovulatory women
are ...
The anterior pituitary response to a gonadotropin-releasing hormone challenge test in normal older reproductive-age women
(Elsevier, 1996-03)
OBJECTIVE: To assess the pituitary responsiveness to GnRH stimulation of
premenopausal women relative to age. DESIGN: Older and younger
reproductive-age women underwent the GnRH stimulation test in the early
follicular phase of the menstrual cycle. SETTING: Female subjects in an
academic research ...
Abnormal patterns of pulsatile luteinizing hormone in women with luteal phase deficiency
(Elsevier, 1984-05)
Luteal phase deficiency is usually a problem of inadequate progesterone
production associated with inadequate ovarian follicular development. The
hypothesis that luteal phase deficiency results from an abnormal secretion
pattern of luteinizing hormone (LH) was tested in these women. To this
end, ...
The importance of luteinizing hormone in the control of inhibin and progesterone secretion by the human corpus luteum
(Endocrine Society, 1989-06)
Serum inhibin levels rise markedly during the luteal phase of the human
menstrual cycle and are closely correlated with serum progesterone (P)
levels, suggesting that the corpus luteum (CL) secretes inhibin. While FSH
is the major regulator of inhibin secretion by the granulosa cells, the
control ...
Luteal phase deficiency: characterization of reproductive hormones over the menstrual cycle
(Endocrine Society, 1989-10)
The recurrent deficiency of progesterone (P) secretion by the corpus
luteum has been associated with infertility and habitual abortion and
given the clinical diagnosis of luteal phase deficiency (LPD). There is
evidence that both follicular and luteal phase abnormalities can result in
LPD cycles. ...
Serum inhibin levels during the periovulatory interval in normal women: relationships with sex steroid and gonadotrophin levels
(Blackwell Publishing, 1990-01)
Inhibin is a gonadal glycoprotein believed to be important in the
regulation of pituitary FSH secretion and/or to function as a paracrine
factor within the ovary and testis. We studied serum levels of inhibin,
oestradiol (E2), progesterone (P), FSH and LH during the periovulatory
interval in order ...
Nocturnal slowing of pulsatile luteinizing hormone secretion in women during the follicular phase of the menstrual cycle
(Endocrine Society, 1985-07)
The gonadotropin secretion pattern in normal reproductive age women (n =
5) was evaluated for the presence of a circadian rhythm. The women
volunteered for a series of 24-h admissions in different phases of their
menstrual cycles (early follicular, late follicular, and midluteal).
Plasma LH and FSH ...
Luteal phase deficiency: abnormal gonadotropin and progesterone secretion patterns
(Endocrine Society, 1989-10)
Luteal phase deficiency (LPD) is a reproductive disorder associated with
infertility and spontaneous abortion. This study was undertaken to
determine whether LPD might be related to an abnormal pattern of
gonadotropin secretion. We tested this hypothesis by evaluating the
pattern of pulsatile LH ...