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An integrated system for large volume sample processing at the point of care
The emergence of rapid, user-friendly, point-of-care (POC) diagnostic systems is paving the way for better disease diagnosis and control. Lately, there has been a strong emphasis on developing molecular-based systems due to their potential for greatly increased sensitivity and specificity. One of the most critical aspects ...
Trends and Predictors of Virologic Failure Following Suppression on Antiretroviral Therapy among HIV Infected Children in Kenya
Background: There are limited data on the incidence and predictors of virologic failure among HIV infected children on antiretroviral treatment (ART), particularly among children who have previously suppressed virus. We examined incidence, timing, and correlates of virologic failure following suppression in a longitudinal ...
Variation in Effectiveness of HIV Assisted Partner Services by Region, Rural Location and Gender in Kenya: A Cluster Randomized Trial
Introduction Assisted partner services (aPS), a strategy to test and link to care the sexual partners of HIV infected persons, is effective in finding new HIV cases. This study assessed whether the effectiveness of aPS differs by region, rural location and gender in a cluster-randomized controlled trial in Kenya. Methods ...
Assessment of Environmental Contamination with Three Pathogens in a Hospital Laundry Facility
Very little is known about the environmental contamination, due to soiled clinical linens, of hospital laundry facilities. To study this environment, an exposure assessment was performed at an industrial clinical laundry facility in Seattle, WA, USA. Surface swab samples (n=240) from the environment were collected from the ...
Experimental Evaluation of Spray Painter Worker Orientation and Spray Distance Using a Distance Guide to Reduce Airborne Exposure to Hexavalent Chromium Paints and Primers
Hexavalent chromium-based primers and paints, which are used widely in the aerospace industry as anti-corrosive coatings, pose a health risk to painters and other workers exposed to the paints and primers. Hexavalent chromium has been established as a carcinogen associated with cancers of the lung and nasal passages. Moreover, ...
Cardiovascular Health Effects of 100% Fruit Juice Versus Whole Fruit in Postmenopausal Women: Results from the Women’s Health Initiative
Introduction We investigated whether 100% fruit juice and whole fruit were independently related to incident hypertension or incident type 2 diabetes. Methods We included women 50-79 years old enrolled in the Women’s Health Initiative. The risk of incident hypertension was analyzed in 80,539 participants and risk of incident ...
Gender Based Violence and HIV Risk: Mediating Pathways and Strategies for Prevention
The studies within this dissertation address gender-based violence (GBV) and its relationship with risk factors for HIV acquisition in African women. Women exposed to GBV have a higher risk of HIV infection, but the mechanisms for this association are not well understood, and the mechanisms may differ according to the patterns ...
Sexual behavior following a diagnosis of acute HIV in men who have sex with men and in transgender women in the Sabes study in Lima, Peru
Objectives: To determine the impact of early antiretroviral therapy (ART) on risky sexual behavior practices during the acute period of human immunodeficiency virus (HIV) infection and compare the ability of different survey modalities to capture these risky sexual behavior practices. Methods/Study Population: Our study looked ...
Beyond the clinic: Motivations for seeking self-induced and alternative methods of abortion care in North America
Objectives: Recent research finds that self-provided and non-clinical abortions are on the rise, largely due to abortion restrictions. This is a qualitative study with a geographically diverse sample to describe people’s motivations for using and providing alternative abortion outside the formal healthcare system in North ...
Determinants of Contraceptive Use Among Postpartum Adolescents in Western Kenya: A Qualitative Analysis
Objective: To examine influences of contraceptive access and use pre- and postpartum among a group of postpartum adolescents. Design/Setting/Participants: This qualitative study utilizing focus group discussions (FGDs) was conducted between October and November 2013 at 2 public sector hospitals in western Kenya. Participants ...