General Internal Medicine, Department of
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Genetic data and cognitively defined late-onset Alzheimer's disease subgroups
(Nature, 2018-12-04)Categorizing people with late-onset Alzheimer's disease into biologically coherent subgroups is important for personalized medicine. We evaluated data from five studies (total n = 4050, of whom 2431 had genome-wide ... -
Genome-wide summary statistics for cognitively defined late-onset Alzheimer’s disease subgroups
(NIAGADS, 2018-12-19)GWAS meta-analysis summary statistics for case-control analyses of five cognitively defined Alzheimer’s disease subgroups. 1. Controls vs. memory predominant AD 2. Controls vs. visuospatial predominant AD 3. Controls ... -
Genetic data and cognitively defined late-onset Alzheimer’s disease subgroups
(Nature, 2018-12-04)Categorizing people with late-onset Alzheimer's disease into biologically coherent subgroups is important for personalized medicine. We evaluated data from five studies (total n = 4050, of whom 2431 had genome-wide ... -
A Review of the Adverse Effects of Peripheral Alpha-1 Antagonists
(2002)Background: Doxazosin and its role as an antihypertensive agent have come under recent scrutiny as a result of the early termination of that treatment arm in ALLHAT. It is unclear why the cardiovascular (CV) event rate in ...