Network motif analysis of a multi-mode genetic-interaction network

ResearchWorks/Manakin Repository

Search ResearchWorks


Advanced Search

Browse

My Account

Statistics

Related Information

Network motif analysis of a multi-mode genetic-interaction network

Show full item record

Title: Network motif analysis of a multi-mode genetic-interaction network
Author: Taylor, R. James; Siegel, Andrew F.; Galitski, Timothy
Abstract: Different modes of genetic interaction indicate different functional relationships between genes. The extraction of biological information from dense multi-mode genetic-interaction networks demands appropriate statistical and computational methods. We developed such methods and implemented them in open-source software. Motifs extracted from multi-mode genetic-interaction networks form functional subnetworks, highlight genes dominating these subnetworks, and reveal genetic reflections of the underlying biochemical system.
URI: http://genomebiology.com/2007/8/8/R160
http://hdl.handle.net/1773/15525

Files in this item

Files Size Format View
gb-2007-8-8-r160.pdf 449.6Kb PDF View/Open

This item appears in the following Collection(s)

Show full item record