Browsing Research in Reproduction and Contraception, Center for by Title
Now showing items 159-178 of 220
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Quantitative (stereological) study of the normal spermatogenesis in the adult monkey (Macaca fascicularis)
(American Society of Andrology, 1997-11)Germ cell and Sertoli cell numbers were estimated in six normal adult monkeys (Macaca fascicularis) using a contemporary unbiased and efficient stereological method--the optical disector. The data was used ... -
Quantitative and qualitative changes in serum luteinizing hormone after injectable testosterone undecanoate treatment in hypogonadal men
(Blackwell Publishing, 2000-03)AIM: To clarify the immuno-active LH (i-LH) and bioactive LH (b-LH) responses and qualitative changes in the circulating LH to testosterone undecanoate (TU) injection. METHODS: Eight men with Klinefelter's ... -
Recombinant human activin-A stimulates basal FSH and GnRH-stimulated FSH and LH release in the adult male macaque, Macaca fascicularis
(Endocrine Society, 1989-11)Activin-A is a homodimer of the beta A inhibin subunit that stimulates FSH secretion by pituitary cells in vitro; however, the physiological relevance of this effect is unknown. We have examined whether ... -
Regulation of galanin and gonadotropin-releasing hormone gene expression in the hypothalamus and basal forebrain of the rat
(Elsevier, 1994-12)Galanin is a cotransmitter in GnRH neurons and is thought to play a role in the control of gonadotropin secretion. The aim of our research has been to learn how galanin mRNA is regulated in GnRH neurons with ... -
Regulation of galanin gene expression in gonadotropin-releasing hormone neurons during the estrous cycle of the rat
(Endocrine Society, 1993-04)Galanin is colocalized with GnRH in neurons of the hypothalamus and basal forebrain of female rats, and this neuropeptide may play a role in the generation of the midcycle surge of gonadotropin secretion. We ... -
Regulation of gonadotropin-releasing hormone (GnRH) and galanin gene expression in GnRH neurons during lactation in the rat [published erratum appears in Endocrinology 1994 Jan;134(1):498]
(Endocrine Society, 1993-09)Galanin is colocalized with GnRH, and its expression in these neurons is enhanced at proestrus, a time of activation of GnRH neurons. We tested the hypothesis that the expression of both the GnRH and galanin ... -
Regulation of hypothalamic neuropeptide-Y neurons by growth hormone in the rat
(Endocrine Society, 1996-04)GH is thought to exert a short-loop feedback action on the hypothalamic somatostatin- and GH-releasing hormone (GHRH)-containing neurons. The direct actions of GH are mediated through GH receptors. In the ... -
Regulation of hypothalamic proopiomelanocortin mRNA by leptin in ob/ob mice
(Endocrine Society, 1997-11)The hormone leptin acts on the brain to regulate feeding, metabolism, and reproduction; however, its cellular targets and molecular mechanisms of action remain to be fully elucidated. The melanocortins, which ... -
Regulation of Kiss1 gene expression in the brain of the female mouse
(Endocrine Society, 2005-09)The Kiss1 gene encodes a family of neuropeptides called kisspeptins, which activate the receptor G protein-coupled receptor-54 and play a role in the neuroendocrine regulation of GnRH secretion. We examined ... -
Regulation of luteinizing hormone pulse frequency and amplitude by testosterone in the adult male rat
(Endocrine Society, 1982-12)Our objective was to gain a better understanding of the role of testosterone (T) in regulating the minute to minute dynamics of LH secretion in the adult male rat. To this end, we examined the patterns of ... -
Regulation of somatostatin and growth hormone-releasing hormone gene expression in the rat brain
(Elsevier, 1990-09)We have studied the regulation of somatostatin (SS) and growth hormone-releasing hormone (GHRH) gene expression in the brain of the laboratory rat. We report that hypophysectomy in the adult male reduces SS ... -
Regulation of testicular function in men: implications for male hormonal contraceptive development
(Elsevier, 2003-06)In the adult male, the testes produce both sperm and testosterone. The function of the testicles is directed by the central nervous system and pituitary gland. Precise regulation of testicular function is ... -
Reifenstein's syndrome: investigation of linkage to X-chromosomal loci
(Blackwell Publishing, 1974) -
Relationship between serum gonadotropins and spermatogenic suppression in men undergoing steroidal contraceptive treatment
(Endocrine Society, 2004-01)This study aimed to establish whether the degree of suppression of serum FSH and LH was related to sperm concentration in three testosterone (T) plus progestin contraceptive regimens. We measured serum FSH ... -
Relationship between testosterone supplementation and insulin-like growth factor-I levels and cognition in healthy older men
(Elsevier, 2004-01)BACKGROUND: Our laboratory has previously reported that testosterone (T) administration to older men significantly improves cognitive function. This study examined potential changes in insulin-like growth ... -
Reproductive ageing and ovarian function: is the early follicular phase FSH rise necessary to maintain adequate secretory function in older ovulatory women?
(Oxford University Press, 2005-01)BACKGROUND: Serum FSH elevations and decreases in inhibin B have been consistently demonstrated in the early follicular phase of cycles in women of advanced reproductive age. However, secretory products of ... -
Reproductive aging: accelerated ovarian follicular development associated with a monotropic follicle-stimulating hormone rise in normal older women
(Endocrine Society, 1996-03)Women experience a decline in fertility that precedes the menopause by several years. Previous studies have demonstrated a monotropic rise in FSH associated with reproductive aging: however, the mechanism of ... -
A role for galanin-like peptide in the integration of feeding, body weight regulation, and reproduction in the mouse
(Endocrine Society, 2003-03)Galanin-like peptide (GALP) shares sequence homology with galanin and binds to galanin receptors in vitro. GALP neurons in the arcuate nucleus coexpress leptin receptors, and GALP mRNA expression is up-regulated ... -
A role for kisspeptins in the regulation of gonadotropin secretion in the mouse
(Endocrine Society, 2004-09)Kisspeptins are products of the KiSS-1 gene, which bind to a G protein-coupled receptor known as GPR54. Mutations or targeted disruptions in the GPR54 gene cause hypogonadotropic hypogonadism in humans and ... -
The role of galanin and its receptor in the feedback regulation of growth hormone secretion
(Endocrine Society, 1996-12)GH controls its own secretion through a mechanism involving short-loop feedback regulation of the synthesis and release of GH-releasing hormone (GHRH). GHRH neurons coexpress the peptide galanin, but the ...