Browsing Research in Reproduction and Contraception, Center for by Title
Now showing items 142-161 of 220
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Packaging paternal chromosomes with protamine [comment]
(Nature Publishing Group, 2001-05) -
A pharmacokinetic study of injectable testosterone undecanoate in hypogonadal men
(American Society of Andrology, 1998-11)Testosterone undecanoate (TU) provides testosterone (T) replacement for hypogonadal men when administered orally but requires multiple doses per day and produces widely variable serum T levels. We investigated ... -
Phenotypic analysis of mice deficient in the type 2 galanin receptor (GALR2)
(American Society for Microbiology, 2005-06)Galanin is a neuropeptide implicated in the regulation of feeding, reproduction, cognition, nociception, and seizure susceptibility. There are three known galanin receptor (GALR) subtypes (GALR1, GALR2, and ... -
Physiological levels of estradiol stimulate plasma high density lipoprotein2 cholesterol levels in normal men
(Endocrine Society, 1994-04)Premenopausal women have a lower risk of coronary artery disease than men or postmenopausal women; estrogens are thought to contribute to this lower risk. Administration of exogenous estrogen to post-menopausal ... -
The physiological significance of pulsatile LHRH secretion in man: gonadotrophin responses to physiological doses of pulsatile versus continuous LHRH administration
(Blackwell Publishing, 1991-02)This study tested whether pulsatile LHRH stimulation of the pituitary is required for normal gonadotrophin secretion in man. Four men with idiopathic hypogonadotrophic hypogonadism (IHH) and presumed endogenous ... -
Pituitary autonomy in hyperprolactinemic secondary amenorrhea: results of hypothalamic-pituitary testing
(Endocrine Society, 1977-05)Twenty-seven women with secondary amenorrhea of greater than six months duration were subjected to multiple testing of hypothalamo-pituitary function. They were divided into normo-prolactinemic (Group 1 mean ... -
Pituitary-thyroid responses to 4-hour constant infusions of thyrotropin releasing hormone in man
(Endocrine Society, 1977-11) -
Plzf is required in adult male germ cells for stem cell self-renewal
(Nature Publishing Group, 2004-06)Adult germline stem cells are capable of self-renewal, tissue regeneration and production of large numbers of differentiated progeny. We show here that the classical mouse mutant luxoid affects adult germline ... -
Post-transcriptional control of gene expression during spermatogenesis
(Elsevier, 1998-08)The synthesis and storage of mRNAs prior to their translation is a necessity during spermatogenesis as global transcription ceases several days prior to the completion of spermatid differentiation. ... -
Preoperative supraphysiological testosterone in older men undergoing knee replacement surgery
(Blackwell Publishing, 2002-10)OBJECTIVES: Older patients undergoing knee replacement surgery can recover more slowly than younger patients and require extended rehabilitation. Because administration of supraphysiological testosterone (T) ... -
Preservation of fertility despite subnormal gonadotropin and testosterone levels after cessation of pulsatile gonadotropin-releasing hormone therapy in a man with Kallmann's syndrome
(Elsevier, 1994-02)A man with IHH and anosmia presented in 1980. He was successfully treated with various hormonal regimens; four children were conceived with hCG or pulsatile GnRH therapy. The patient discontinued GnRH after ... -
Progesterone modulation of pulsatile luteinizing hormone secretion in normal women
(Endocrine Society, 1984-02)Recent studies show that the frequency and amplitude of pulsatile LH secretion change during the normal human menstrual cycle; however, the neuroendocrine mechanisms underlying these changes are poorly ... -
Prolactin secretion and corpus luteum function in women with luteal phase deficiency
(Endocrine Society, 1991-05)Luteal phase deficiency (LPD) as a clinical infertility problem is considered to have a heterogeneous etiology. Hyperprolactinemia has long been considered a causative factor of LPD. In this context we ... -
Proopiomelanocortin neurons are direct targets for leptin in the hypothalamus
(Endocrine Society, 1997-10)Leptin is a protein product of the obese (ob) gene, which is secreted by adipocytes and functions as a satiety factor to regulate food intake. The expression of the leptin receptor in several hypothalamic ... -
Proscar: five-year experience
(Elsevier, 1995)We assessed the long-term safety and efficacy of finasteride, an orally active 5 alpha-reductase inhibitor, in 2 previously reported groups of patients with symptomatic benign prostatic hyperplasia (BPH). ... -
Prostate-sparing effects in primates of the potent androgen 7alpha-methyl-19-nortestosterone: a potential alternative to testosterone for androgen replacement and male contraception
(Endocrine Society, 1998-12)7alpha-Methyl-19-nortestosterone (MENT) is a potent synthetic androgen that cannot be converted to dihydrotestosterone. In this study we determined the relative androgenic, antigonadotropic, and anabolic ... -
Pubertal changes in gonadotropin-releasing hormone and proopiomelanocortin gene expression in the brain of the male rat
(Endocrine Society, 1989-04)Pubertal development in mammals is in part attributable to a brain-dependent process, whereby increased pulsatile GnRH secretion leads to the awakening of the entire reproductive system. However, the brain ... -
Quantitative (stereological) study of the normal spermatogenesis in the adult monkey (Macaca fascicularis)
(American Society of Andrology, 1997-11)Germ cell and Sertoli cell numbers were estimated in six normal adult monkeys (Macaca fascicularis) using a contemporary unbiased and efficient stereological method--the optical disector. The data was used ... -
Quantitative and qualitative changes in serum luteinizing hormone after injectable testosterone undecanoate treatment in hypogonadal men
(Blackwell Publishing, 2000-03)AIM: To clarify the immuno-active LH (i-LH) and bioactive LH (b-LH) responses and qualitative changes in the circulating LH to testosterone undecanoate (TU) injection. METHODS: Eight men with Klinefelter's ... -
Recombinant human activin-A stimulates basal FSH and GnRH-stimulated FSH and LH release in the adult male macaque, Macaca fascicularis
(Endocrine Society, 1989-11)Activin-A is a homodimer of the beta A inhibin subunit that stimulates FSH secretion by pituitary cells in vitro; however, the physiological relevance of this effect is unknown. We have examined whether ...