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Browsing Research in Reproduction and Contraception, Center for by Title
Now showing items 87-106 of 220
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Hormonal responses to a potent gonadotropin hormone-releasing hormone antagonist in normal elderly men
(Endocrine Society, 1990-10)GnRH analogs, both agonists and antagonists, have potential use in androgen-dependent diseases of older men, such as prostatic cancer and benign prostatic hyperplasia. Previous experience with agonists of ... -
Identification of ZFR, an ancient and highly conserved murine chromosome-associated zinc finger protein
(Elsevier, 1999-03-04)In a screen for RNA binding proteins expressed during murine spermatogenesis, we cloned a novel, ancient zinc finger protein possessing a region common to a small class of RNA binding proteins. Zfr (zinc ... -
Immature spermatids are not prevalent in semen from men who are receiving androgen-based contraceptive regimens
(Elsevier, 1998-01)OBJECTIVE: To determine whether immature spermatids increase in semen in response to hormonal contraceptive treatments. Such a finding would support the existence of a defect in spermiogenesis, which in turn ... -
Immunohistochemical localization of androgen receptors in the rat testis: evidence for stage-dependent expression and regulation by androgens
(Endocrine Society, 1994-09)Androgens are essential for the maintenance of normal spermatogenesis in the rat. We assessed the sites, developmental pattern, and hormonal control of androgen receptors (AR) in the rat testis. Adult male ... -
The immunoreactive inhibin secretion pattern in the midluteal phase: relationships with luteinizing hormone and progesterone
(Blackwell Publishing, 1990-12)With the development of a sensitive radioimmunoassay for inhibin, luteal phase inhibin levels have been noted to parallel progesterone levels and be acutely dependent upon luteinizing hormone (LH) stimulation. ... -
Impairment of Spermatogonial Development and Spermiation after Testosterone-Induced Gonadotropin Suppression in Adult Monkeys (Macaca fascicularis)
(The Endocrine Society, 2001-04)Human male hormonal contraceptive regimens do not consistently induce azoospermia, and the basis of this variable response is unclear. This study used nine adult macaque monkeys (Macaca fascicularis) given ... -
The importance of luteinizing hormone in the control of inhibin and progesterone secretion by the human corpus luteum
(Endocrine Society, 1989-06)Serum inhibin levels rise markedly during the luteal phase of the human menstrual cycle and are closely correlated with serum progesterone (P) levels, suggesting that the corpus luteum (CL) secretes inhibin. ... -
The importance of signal pattern in the transmission of endocrine information: pituitary gonadotropin responses to continuous and pulsatile gonadotropin-releasing hormone
(Endocrine Society, 1991-06)We tested the hypothesis that pulsatile GnRH stimulation of the pituitary is required for normal gonadotropin secretion in humans. We administered GnRH in pulsatile and continuous regimens in varying order ... -
Increased frequency of pulsatile luteinizing hormone-releasing hormone administration selectively decreases follicle-stimulating hormone levels in men with idiopathic azoospermia
(Elsevier, 1986-03)Men with idiopathic azoo-oligospermia and selective elevations of follicle-stimulating hormone (FSH) levels have evidence for decreased luteinizing hormone-releasing hormone (LH-RH) pulse frequency. We ... -
Increases in serum concentrations of follicle-stimulating hormone (FSH) during thyrotrophin-releasing hormone (TRH) infusions in normal men
(Blackwell Publishing, 1977-11)Increases in serum FSH values to approximately 50% above basal concentrations were found during TRH infusions of 2.0 microgram/min into normal men (n = 10). These increases could not be explained by ... -
Induction of galanin gene expression in gonadotropin-releasing hormone neurons with puberty in the rat
(Endocrine Society, 1994-10)The onset of puberty reflects the developmental activation of GnRH neurons whose secretory activity awakens the reproductive axis; however, the cellular mechanisms involved in this activational process remain ... -
Induction of galanin mRNA in GnRH neurons by estradiol and its facilitation by progesterone
(Blackwell Publishing, 1996-03)On the day of proestrus in the rat, rising plasma levels of estradiol (E) act in concert with progesterone (P) to trigger a preovulatory release of gonadotropins. Cellular levels of galanin mRNA in GnRH neurons ... -
The induction of premature luteolysis in normal women--follicular phase luteinizing hormone secretion and corpus luteum function in the subsequent cycle
(Elsevier, 1991-04)Women with luteal phase deficiency have been shown to have an increased frequency of luteinizing hormone pulses in the early follicular phase of the menstrual cycle. Because progesterone is known to modulate ... -
Inhibin-B: a likely candidate for the physiologically important form of inhibin in men
(Endocrine Society, 1996-04)Inhibin is a glycoprotein hormone that is defined on the basis of inhibition of pituitary FSH production, However, previous data have not shown any correlation between RIA measurements of inhibin and FSH in ... -
Inhibition of fetal growth and survival by testosterone administration to pregnant sheep
(Elsevier, 1978-03)Testosterone (as testosterone enanthate, 250 mg i.m. every 2 wk) was administered to pregnant ewes (n = 16), and injections of vehicle were used in 10 control pregnant ewes between days 75 of gestation and ... -
Inhibition of steroid-induced galanin mRNA expression in GnRH neurons by specific NMDA-receptor blockade
(Blackwell Publishing, 1996-03)Galanin mRNA levels in GnRH neurons increase in association with a steroid-induced LH surge in female rats. Both the steroid-induced LH surge and the concomitant increase of galanin mRNA in GnRH neurons are ... -
Intramuscular testosterone enanthate plus very low dosage oral levonorgestrel suppresses spermatogenesis without causing weight gain in normal young men: a randomized clinical trial
(American Society of Andrology, 2005-05)The development of a safe, well-tolerated, effective, and reversible male hormonal contraceptive would be a major clinical advance for couples planning their family size and for control of population growth. ... -
Intratesticular testosterone concentrations comparable with serum levels are not sufficient to maintain normal sperm production in men receiving a hormonal contraceptive regimen
(American Society of Andrology, 2004-11)Intratesticular testosterone (ITT) is thought to play a key role in the control of spermatogenesis in man but is rarely measured. The purposes of this study were 1) to examine the relationship between ...