Browsing Research in Reproduction and Contraception, Center for by Author "Cunningham, Matthew J."

Now showing items 1-7 of 7

    • Cloning and distribution of galanin-like peptide mRNA in the hypothalamus and pituitary of the macaque 

      Steiner, Robert A.; Cunningham, Matthew J.; Scarlett, Jarrad M. (Endocrine Society, 2002-03)
      Galanin-like peptide (GALP) is a newly discovered hypothalamic neuropeptide, which is regulated by leptin and implicated in the regulation of GnRH secretion in the rodent. We searched the human genome ...

    • Distribution and regulation of galanin-like peptide (GALP) in the hypothalamus of the mouse 

      Johnson, Laura L.; Clifton, Donald K.; Li, Dorothy; Steiner, Robert A.; Teklemichael, Dawit N.; Krasnow, Stephanie M.; Jureus, Anders; Cunningham, Matthew J. (Endocrine Society, 2001-12)
      Galanin-like peptide (GALP) is a newly discovered molecule whose expression in the brain is confined to the arcuate nucleus and median eminence. In the rat, cellular levels of GALP mRNA are reduced by fasting ...

    • Galanin-like peptide (GALP) is a target for regulation by leptin in the hypothalamus of the rat 

      Clifton, Donald K.; McClain, Molly E.; Steiner, Robert A.; Jureus, Anders; Cunningham, Matthew J. (Endocrine Society, 2000-07)
      Galanin-like peptide (GALP), which was recently isolated from the porcine hypothalamus, shares sequence homology with galanin and binds with high affinity to galanin receptors. To study the distribution and ...

    • Galanin-like peptide as a possible link between metabolism and reproduction in the macaque 

      Scarlett, Jarrad M.; Smith, M. Susan; Grove, Kevin L.; Clifton, Donald K.; Cameron, Judy L.; Plant, Tony M.; Steiner, Robert A.; Cunningham, Matthew J.; Shahab, Muhammad (Endocrine Society, 2004-04)
      Galanin-like peptide (GALP) is a hypothalamic neuropeptide that has been implicated in the control of feeding, metabolism, and reproduction. The goal of this study was to examine the effects of central infusions ...

    • Regulation of Kiss1 gene expression in the brain of the female mouse 

      Smith, Jeremy T.; Steiner, Robert A.; Cunningham, Matthew J.; Clifton, Donald K.; Rissman, Emilie F. (Endocrine Society, 2005-09)
      The Kiss1 gene encodes a family of neuropeptides called kisspeptins, which activate the receptor G protein-coupled receptor-54 and play a role in the neuroendocrine regulation of GnRH secretion. We examined ...

    • A role for kisspeptins in the regulation of gonadotropin secretion in the mouse 

      Clifton, Donald K.; Steiner, Robert A.; Smith, Jeremy T.; Gottsch, Michelle L.; Crowley, W. F.; Acohido, B. V.; Cunningham, Matthew J.; Popa, Simina M.; Seminara, S. (Endocrine Society, 2004-09)
      Kisspeptins are products of the KiSS-1 gene, which bind to a G protein-coupled receptor known as GPR54. Mutations or targeted disruptions in the GPR54 gene cause hypogonadotropic hypogonadism in humans and ...

    • Serotonergic neurons are targets for leptin in the monkey 

      Clifton, Donald K.; Rickard, Diana G.; Steiner, Robert A.; Finn, Patricia D.; Cunningham, Matthew J. (Endocrine Society, 2001-01)
      Leptin is a secretory product of adipocytes that has been shown to affect food intake, metabolism, and reproduction. One site of leptin's action is the central nervous system, where the leptin receptor (Ob-R) ...