Browsing Research in Reproduction and Contraception, Center for by Author "Meriggiola, M. Cristina"
Now showing items 1-11 of 11
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Annual patterns of luteinizing hormone, follicle stimulating hormone, testosterone and inhibin in normal men
Bremner, William J.; Paulsen, C. Alvin; Meriggiola, M. Cristina; Noonan, Elizabeth A. (Oxford University Press, 1996-02)Reproductive functions in most animals demonstrate seasonal fluctuations that allow young to be born at a time of the year favourable for their survival. Whether there is a seasonal change in the human ... -
A combined regimen of cyproterone acetate and testosterone enanthate as a potentially highly effective male contraceptive
Valdiserri, Alessandro; Pavani, Anna; Paulsen, C. Alvin; Capelli, Maurizio; Motta, Roberto; Incorvaia, Loredana; Flamigni, Carlo; Meriggiola, M. Cristina; Bremner, William J. (Endocrine Society, 1996-08)In this study we tested the effectiveness of the combined administration of cyproterone acetate (CPA) and testosterone enanthate (TE) in suppressing spermatogenesis. After a control phase of 3 months, 15 ... -
Follistatin decreases activin-stimulated FSH secretion with no effect on GnRH-stimulated FSH secretion in prepubertal male monkeys
Mather, Jennie P.; Bremner, William J.; Dahl, Kristine D.; Meriggiola, M. Cristina (Endocrine Society, 1994-04)Follistatin is an activin-binding glycoprotein that decreases FSH secretion in vitro and in vivo in rats. The mechanism by which follistatin acts is unclear, but it has been suggested that it may bind ... -
Higher testosterone dose impairs sperm suppression induced by a combined androgen-progestin regimen
Morselli-Labate, Antonio M.; Bremner, William J.; Meriggiola, M. Cristina; Costantino, Antonietta (American Society of Andrology, 2002-09)In this study we compared the effects of high-dose and low-dose testosterone enanthate (TE) administered with the same dose of cyproterone acetate (CPA). Eighteen men aged 21-45 were treated with CPA 5 mg/day ... -
Low dose of cyproterone acetate and testosterone enanthate for contraception in men
Di Cintio, Giulio; Costantino, Antonietta; Flamigni, Carlo; Meriggiola, M. Cristina; Bremner, William J. (Oxford University Press, 1998-05)After a control phase, 10 normal men received cyproterone acetate (CPA) at a dose of 25 mg/day (CPA-25; n=5) or 12.5 mg/day (CPA-12.5; n=5) plus testosterone enanthate (TE) 100 mg/week, for 16 weeks. Throughout ... -
Norethisterone enanthate plus testosterone undecanoate for male contraception: effects of various injection intervals on spermatogenesis, reproductive hormones, testis, and prostate
Meriggiola, M. Cristina; Ernst, M.; Costantino, Antonietta; Pelusi, G.; Saad, F.; Bertaccini, Alessandro; D'Emidio, L.; Bremner, William J.; Morselli-Labate, Antonio M.; Kirsch, B.; Martorana, G.; Rudolph, I. (Endocrine Society, 2005-05)The goal of this study was to find the most favorable injection interval of norethisterone enanthate (NETE) plus testosterone undecanoate (TU) in terms of gonadotropin, sperm suppression, and prostatic effects. ... -
An oral regimen of cyproterone acetate and testosterone undecanoate for spermatogenic suppression in men
Pavani, Anna; Costantino, Antonietta; Flamigni, Carlo; Capelli, Maurizio; Meriggiola, M. Cristina; Bremner, William J. (Elsevier, 1997-11)OBJECTIVE: To test the effectiveness, safety, and reversibility of the combined administration of cyproterone acetate and T undecanoate. DESIGN: Open clinical trial. SETTING: Healthy volunteers in an academic ... -
Relationship between serum gonadotropins and spermatogenic suppression in men undergoing steroidal contraceptive treatment
Ugoni, Antony; Bremner, William J.; Pruysers, Enid; Meriggiola, M. Cristina; Anawalt, Bradley D.; Matsumoto, Alvin M.; McLachlan, Robert I.; Robertson, David M. (Endocrine Society, 2004-01)This study aimed to establish whether the degree of suppression of serum FSH and LH was related to sperm concentration in three testosterone (T) plus progestin contraceptive regimens. We measured serum FSH ... -
Testosterone enanthate at a dose of 200 mg/week decreases HDL-cholesterol levels in healthy men
Marcovina, Santica M.; Meriggiola, M. Cristina; Bremner, William J.; Paulsen, C. Alvin (Blackwell Publishing, 1995-10)The concept that androgen alone can provide an effective male contraceptive has been tested in a multicentre, multiphase trial by the World Health Organization. Results from this trial showed that an ester ... -
Testosterone undecanoate maintains spermatogenic suppression induced by cyproterone acetate plus testosterone undecanoate in normal men
Huebler, Doris; Pelusi, C.; Pelusi, G.; Meriggiola, M. Cristina; Bremner, William J.; Morselli-Labate, Antonio M.; Costantino, Antonietta; Cerpolini, S.; Kirsch, B.; Bertaccini, Alessandro (Endocrine Society, 2003-12)In this study we evaluated whether testosterone undecanoate (TU), alone or combined with low dose cyproterone acetate (CPA), can maintain spermatogenic suppression induced by higher doses of CPA plus TU. ... -
Twenty-one day administration of dienogest reversibly suppresses gonadotropins and testosterone in normal men
Oettel, Michael; Flamigni, Carlo; Costantino, Antonietta; Meriggiola, M. Cristina; Morselli-Labate, Antonio M.; Huebler, Doris; Bremner, William J.; Bertaccini, Alessandro; Kaufmann, Guenter (Endocrine Society, 2002-05)Androgen-progestin combinations are promising male contraceptive regimens. Optimization of these regimens includes the development of new progestins with more favorable biological properties. In this context ...