Weigle, David S.; Kuijper, Joseph L.; Steiner, Robert A.; Clifton, Donald K.; Cheung, Clement C.; Thornton, Janice E.(Endocrine Society, 1997-02)
The timing of puberty onset in mammals is tightly coupled to the animal's
nutritional and metabolic state. We conducted two experiments to test the
hypothesis that leptin acts as a metabolic signal for the ...
Steiner, Robert A.; Clifton, Donald K.; Thornton, Janice E.; Cheung, Clement C.(Endocrine Society, 1997-11)
The hormone leptin acts on the brain to regulate feeding, metabolism, and
reproduction; however, its cellular targets and molecular mechanisms of
action remain to be fully elucidated. The melanocortins, which ...