Browsing Genome Sciences, Department of by Author "Ringwald, Pascal"
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A database of antimalarial drug resistance
Sibley, Carol Hopkins; Ringwald, Pascal (2006)A large investment is required to develop, license and deploy a new antimalarial drug. Too often, that investment has been rapidly devalued by the selection of parasite populations resistant to the drug action. To understand ... -
World Antimalarial Resistance Network (WARN) II: In vitro antimalarial drug susceptibility
Bacon, David J.; Jambou, Ronan; Fandeur, Thierry; Le Bras, Jacques; Wongsrichanalai, Chansuda; Fukuda, Mark M.; Ringwald, Pascal; Sibley, Carol Hopkins; Kyle, Dennis E. (2007)Intrinsic resistance of Plasmodium falciparum is clearly a major determinant of the clinical failure of antimalarial drugs. However, complex interactions between the host, the parasite and the drug obscure the ability to ...