Browsing Department of Genome Sciences Faculty Papers by Title
Now showing items 12-16 of 16
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The rationale and plan for creating a World Antimalarial Resistance Network (WARN)
(2007)Drug resistant malaria was a major factor contributing to the failure of a worldwide campaign to eradicate malaria in the last century, and now threatens the large investment being made by the global community in the rollout ... -
Resolving multicopy duplications de novo using polyploid phasing
(Springer, 2017-05)While the rise of single-molecule sequencing systems has enabled an unprecedented rise in the ability to assemble complex regions of the genome, long segmental duplications in the genome still remain a challenging ... -
World Antimalarial Resistance Network (WARN) II: In vitro antimalarial drug susceptibility
(2007)Intrinsic resistance of Plasmodium falciparum is clearly a major determinant of the clinical failure of antimalarial drugs. However, complex interactions between the host, the parasite and the drug obscure the ability to ... -
World Antimalarial Resistance Network (WARN) III: Molecular markers for drug resistant malaria
(2007)Molecular markers for drug resistant malaria represent public health tools of great but mostly unrealized potential value. A key reason for the failure of molecular resistance markers to live up to their potential is that ... -
World Antimalarial Resistance Network (WARN) IV: Clinical pharmacology
(2007)A World Antimalarial Resistance Network (WARN) database has the potential to improve the treatment of malaria, through informing current drug selection and use and providing a prompt warning of when treatment policies need ...