Neurology, Department of
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Recent Submissions
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Data in support of manuscript: Huntingtin loss in hepatocytes is associated with altered metabolism, adhesion, and liver zonation
(2023-07-17)Huntington’s disease arises from a toxic gain of function in the huntingtin (HTT) gene. As a result, many HTT-lowering therapies are being pursued in clinical studies, including those that reduce HTT RNA and protein ... -
Interpreting cerebrospinal fluid pleocytosis in HIV in the era of potent antiretroviral therapy
(2007)Background: Cerebrospinal fluid (CSF) pleocytosis may be seen in asymptomatic HIV-infected individuals. This finding complicates interpretation of CSF abnormalities when such individuals are evaluated for other central ... -
Hormonal exposures and the risk of intracranial meningioma in women: a population-based case-control study
(2006)Background: The role of exogenous hormone exposures in the development of meningioma is unclear, but these exposures have been proposed as one hypothesis to explain the over-abundance of such tumors in women. Methods: The ... -
Unloaded Speed of Shortening in Voltage-Clamped Intact Skeletal Muscle Fibers from wt, mdx, and Transgenic Minidystrophin Mice Using a Novel High-Speed Acquisition System
(2008)Skeletal muscle unloaded shortening has been indirectly determined in the past. Here, we present a novel high-speed optical tracking technique that allows recording of unloaded shortening in single intact, voltage-clamped ... -
Enhanced effect of microdystrophin gene transfection by HSV-VP22 mediated intercellular protein transport
(2007)Background: Duchenne musclar dystrophy (DMD) is an X-linked recessive disease caused by mutations of dystrophin gene, there is no effective treatment for this disorder at present. Plasmidmediated gene therapy is a promising ...