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dc.contributor.authorPrehn, Richmond T.en_US
dc.date.accessioned2010-05-06T20:03:41Z
dc.date.available2010-05-06T20:03:41Z
dc.date.issued2005en_US
dc.identifier.citationOn the nature of cancer and why anticancer vaccines don't work. Cancer Cell International. 2005;5(1):25.en_US
dc.identifier.other10.1186/1475-2867-5-25en_US
dc.identifier.urihttp://www.cancerci.com/content/5/1/25en_US
dc.identifier.urihttp://hdl.handle.net/1773/15823
dc.description.abstractIn this essay I suggest that the major difficulty in producing effective anti-cancer vaccines lies in the fact that most cancers have little immunogenicity because of a basic paucity of tumor-specific antigenicity. The lack of antigenicity, despite extensive genomic instability, could be explained if most tumor mutations occur in silenced genes. A further problem is that an immune reaction against tumor antigens, especially in moderate or low amount, may be stimulatory rather than inhibitory to tumor growth.en_US
dc.description.sponsorshipen_US
dc.language.isoen_USen_US
dc.titlePrehn, R. On the nature of cancer and why anticancer vaccines don't worken_US
dc.typeArticleen_US


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