Show simple item record

dc.contributor.authorPrehn, Richmond T.en_US
dc.date.accessioned2010-05-06T20:04:00Z
dc.date.available2010-05-06T20:04:00Z
dc.date.issued2007en_US
dc.identifier.citationPrehn R. Immunostimulation and Immunoinhibition of Premalignant Lesions. Theoretical Biology and Medical Modelling. 2007;4(1):6.en_US
dc.identifier.other10.1186/1742-4682-4-6en_US
dc.identifier.urihttp://www.tbiomed.com/content/4/1/6en_US
dc.identifier.urihttp://hdl.handle.net/1773/15826
dc.description.abstractBackground: The immune reaction may be either stimulatory or inhibitory to tumor growth, depending upon the local ratio of immune reactants to tumor cells. Hypothesis: A tumor-stimulatory immune response may be essential for survival of a neoplasm in vivo and for the biological progression from a premalignant lesion to a malignancy. Neither a positive nor a negative correlation between the magnitude of an immune-cell infiltrate and a cancer's prognosis can reveal whether the infiltrate was stimulating or inhibiting to the tumor's growth unless the position on the nonlinear curve that relates tumor growth to the magnitude of the immune reaction is known. Discussion: This hypothesis is discussed in relation to the development of human malignant melanomas and colorectal cancers.en_US
dc.description.sponsorshipen_US
dc.language.isoen_USen_US
dc.titleImmunostimulation and Immunoinhibition of Premalignant Lesionsen_US
dc.typeArticleen_US


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record