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The Origins of Neurons and use of Glutamatergic Signaling in the Ctenophore: Pleurobrachia bachei
(2012)
Ctnenophores
are
a
group
of
marine,
jelly
like,
comb
bearing
metazoans.
This
phylum
consists
of
an
estimated
100-‐200
species
(Mills
CE,
2012).
Ctenophores
are
similar
to
cnidarians
in
that
they
have
a
homologous
mesoderm
consisting
of
a
jelly
like
substance
called
mesoglea.
They
...
A Quest for novel Signaling Molecules in Pleurobrachia Bachei
(2012)
The evolution of the nervous system is poorly understood, with broad implications in basic neuroscience and regenerative medicine. The unintuitive nervous system of the basal Ctenophores provides an insight into neuronal evolution. We developed a Zero-Click computational pipeline for secretory peptide prediction from raw ...
Brachyury expression in the adult ctenophore, Pleurobrachia bachei
(2012)
Brachyury is a transcription factor important for mesoderm formation in chordates. Ctenophores are basal metazoans with little known about their germ layer organization. For this reason, brachyury was used as a possible mesodermal marker in the ctenophore Pleurobrachia bachei . The gene was cloned and then used for in situ ...
Gone with the Wnts…. The Wnt Signaling Pathway in Pleurobrachia bachei
(2012)
Wnt signaling is known to be critical for proper embryonic development in most
animals studied to date15. But key evolutionary questions on the origin and evolution of
this pathway in the metazoan common ancestor are still unresolved. Recently, the
genome of Pleurobrachia bachei, a member of the early branching metazoan ...
Collagen type IV in the Ctenophore Pleurobrachia bachei
(2012)
The evolution of multicellular animals required the development of epithelial tissues that function in controlling the transport of molecules from one environment to another. Collagen proteins are crucial to the formation of epithelial tissues, and are therefore critical in understanding the origins of multicellularity and ...
Out on a LIM: LIM homeobox genes in the ctenophore Pleurobrachia bachei
(2012)
LIM homeobox (Lhx) gene family consists of six subfamilies of patterning genes which
play a major role in the development of the nervous system and are found only in animals. We
looked at their presence and expression in the ctenophore Pleurobrachia bachei to study their
evolution and development. Ctenophores are among the ...