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Brachyury expression in the adult ctenophore, Pleurobrachia bachei
Brachyury is a transcription factor important for mesoderm formation in chordates. Ctenophores are basal metazoans with little known about their germ layer organization. For this reason, brachyury was used as a possible mesodermal marker in the ctenophore Pleurobrachia bachei . The gene was cloned and then used for in situ ...
Collagen type IV in the Ctenophore Pleurobrachia bachei
The evolution of multicellular animals required the development of epithelial tissues that function in controlling the transport of molecules from one environment to another. Collagen proteins are crucial to the formation of epithelial tissues, and are therefore critical in understanding the origins of multicellularity and ...
The Search for Putative Mesoderm and Muscle Specific Genes in Pleurobrachia bachei
There has been a long debate in the scientific community over the oldest surviving metazoan lineage. Traditionally it has been taught that Porifera, the sponges, occupy that nitche possessing a diploblastic body plan without true organs; however recent phylogentic analysis has suggests that Ctenophora may truly be the ...
Out on a LIM: LIM homeobox genes in the ctenophore Pleurobrachia bachei
LIM homeobox (Lhx) gene family consists of six subfamilies of patterning genes which play a major role in the development of the nervous system and are found only in animals. We looked at their presence and expression in the ctenophore Pleurobrachia bachei to study their evolution and development. Ctenophores are among the ...
The Origins of Neurons and use of Glutamatergic Signaling in the Ctenophore: Pleurobrachia bachei
Ctnenophores are a group of marine, jelly like, comb bearing metazoans. This phylum consists of an estimated 100-‐200 species (Mills CE, 2012). Ctenophores are similar to cnidarians in that they have a homologous mesoderm consisting of a jelly like substance called mesoglea. They ...