Now showing items 11-14 of 14
Brachyury expression in the adult ctenophore, Pleurobrachia bachei
Brachyury is a transcription factor important for mesoderm formation in chordates. Ctenophores are basal metazoans with little known about their germ layer organization. For this reason, brachyury was used as a possible mesodermal marker in the ctenophore Pleurobrachia bachei . The gene was cloned and then used for in situ ...
Gone with the Wnts…. The Wnt Signaling Pathway in Pleurobrachia bachei
Wnt signaling is known to be critical for proper embryonic development in most animals studied to date15. But key evolutionary questions on the origin and evolution of this pathway in the metazoan common ancestor are still unresolved. Recently, the genome of Pleurobrachia bachei, a member of the early branching metazoan ...
Collagen type IV in the Ctenophore Pleurobrachia bachei
The evolution of multicellular animals required the development of epithelial tissues that function in controlling the transport of molecules from one environment to another. Collagen proteins are crucial to the formation of epithelial tissues, and are therefore critical in understanding the origins of multicellularity and ...
Out on a LIM: LIM homeobox genes in the ctenophore Pleurobrachia bachei
LIM homeobox (Lhx) gene family consists of six subfamilies of patterning genes which play a major role in the development of the nervous system and are found only in animals. We looked at their presence and expression in the ctenophore Pleurobrachia bachei to study their evolution and development. Ctenophores are among the ...