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Evaluation of a Computer-Based System using Cell Phones for HIV positive people in Peru

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dc.contributor.advisor Pratt, Wanda en_US Curioso, Walter H. en_US 2012-09-13T17:26:05Z 2012-09-13 2012 en_US
dc.identifier.other Curioso_washington_0250E_10684.pdf en_US
dc.description Thesis (Ph.D.)--University of Washington, 2012 en_US
dc.description.abstract HIV is one of the biggest infectious killers worldwide. To prevent disease progression and avoid development of resistant strains to HIV, people living with HIV must adhere to complicated antiretroviral therapy (ART). Yet, in Peru, where ART has recently been introduced, adherence to HIV treatment has not yet been addressed properly, and no systematic approaches to evaluate or promote adherence to ART exist. For people living with HIV, innovative approaches using information technologies, such as mobile phones, are needed to increase adherence to ART. In my thesis, I proposed the following specific aims: (1) To conduct formative research to assess culturally-specific behavioral messages to be included in the computer-based system; (2) To develop and test an interactive computer-based system using cell phones both to enhance adherence to ART and to deliver HIV transmission risk reduction messages; and (3) To evaluate the impact of the system on ART adherence. To achieve these aims, I conducted a randomized controlled trial of a 12-month intervention, comparing (1) standard-of-care with (2) standard-of-care plus my mobile phone-based system among patients receiving ART at Via Libre, a non-governmental organization established to help people with HIV, and Hospital Nacional Cayetano Heredia, a governmental hospital; both in Lima, Peru. This novel trial adds important evidence to the field of mHealth--the provision of health-related services via mobile communications. The trial is potentially scalable as a prevention strategy by the Ministry of Health, and the results could be applied in other settings, not only for ART, but also to encourage patients to follow long-term treatment plans for other chronic diseases. Furthermore, because the intervention is automated using available information and communication technology, it can be scaled up widely without requiring proportionate and expensive staff resources. en_US
dc.format.mimetype application/pdf en_US
dc.language.iso en_US en_US
dc.rights Copyright is held by the individual authors. en_US
dc.subject adherence; biomedical informatics; HIV; mobile health en_US
dc.subject.other Computer science en_US
dc.subject.other Information technology en_US
dc.subject.other Biomedical and health informatics en_US
dc.title Evaluation of a Computer-Based System using Cell Phones for HIV positive people in Peru en_US
dc.type Thesis en_US
dc.embargo.terms Restrict to UW for 2 years -- then make Open Access en_US
dc.embargo.lift 2014-09-03T17:26:05Z

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