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dc.contributor.advisorFriedman, Carolyn Sen_US
dc.contributor.authorDorfmeier, Eleneen_US
dc.date.accessioned2012-09-13T17:32:35Z
dc.date.available2012-09-13T17:32:35Z
dc.date.issued2012-09-13
dc.date.submitted2012en_US
dc.identifier.otherDorfmeier_washington_0250O_10226.pdfen_US
dc.identifier.urihttp://hdl.handle.net/1773/20742
dc.descriptionThesis (Master's)--University of Washington, 2012en_US
dc.description.abstractVibrio tubiashii (Vt) is a causative agent of vibriosis in molluscan bivalves. Recent re-emergence of vibriosis in economically valuable shellfish, such as the Pacific oyster (Crassostrea gigas) in Washington State, has increased the urgency to understand the ecology of this pathogen. It is currently unknown how predicted environmental changes associated with ocean acidification, such as elevated surface seawater temperature, increased partial pressure of CO2 (pCO2), and Vt abundance will impact marine organismal health and disease susceptibility. This study investigates how environmental cues predicted with ocean acidification influence physiological changes and pathogenicity in Vt. Using laboratory experiments to manipulate temperature and pCO2, we examined how these environmental factors influenced pathogen growth. Larval susceptibility to vibriosis was determined by exposing C. gigas larvae to a combination of elevated pCO2 and Vt concentrations. These experiments provide insight into the environmental parameters that may drive pathogenicity or influence proliferation of the bacterium. Investigation of single and multivariate parameters such as temperature, pCO2, and pathogen levels will help assess how predicted shifts in ocean conditions can impact shellfish survival and disease resistance.en_US
dc.format.mimetypeapplication/pdfen_US
dc.language.isoen_USen_US
dc.rightsCopyright is held by the individual authors.en_US
dc.subjectVibrio tubiashii; ocean acidification; Pacific oyster; vibriosisen_US
dc.subject.otherAnimal diseasesen_US
dc.subject.otherBiologyen_US
dc.subject.otherBioinformaticsen_US
dc.subject.otherFisheriesen_US
dc.titleOcean acidification and disease: How will a changing climate impact Vibrio tubiashii growth and pathogenicity to Pacific oyster larvae?en_US
dc.typeThesisen_US
dc.embargo.termsNo embargoen_US


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