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dc.contributor.advisorNemhauser, Jennifer L.en_US
dc.contributor.authorLilley, Jodi Lorraine Stewarten_US
dc.date.accessioned2013-07-23T18:26:58Z
dc.date.available2013-07-23T18:26:58Z
dc.date.issued2013-07-23
dc.date.submitted2013en_US
dc.identifier.otherLilley_washington_0250E_11412.pdfen_US
dc.identifier.urihttp://hdl.handle.net/1773/22777
dc.descriptionThesis (Ph.D.)--University of Washington, 2013en_US
dc.description.abstractPhotomorphogenesis has two stages. First, seedlings detect light and open their embryonic leaves (cotyledons). Second, seedlings optimize their light environment by regulated elongation of the embryonic stem (hypocotyl). Several hormones, including auxin, brassinosteroids (BR) and gibberellins (GA), orchestrate the growth of the seedlings stem. The work presented in this dissertation used time-lapse imaging coupled with molecular biology to investigate the dynamics of these hormones across photomorphogenesis. These studies revealed distinct growth dynamics during each stage, in addition to changes in growth hormone sensitivity across these stages. For example, the interaction between the brassinosteroid and gibberellin pathways is quite different in early versus late promotion of seedling growth. In late stages of seedling development, the hormone auxin and the <italic>PHYTOCHROME INTERACTING FACTOR (PIF)</italic> family of transcription factors mediate an endogenous carbon-sensing mechanism regulating `light-foraging' hypocotyl growth. Dynamic analysis of growth, protein abundance and gene expression support a `regulatory relay' model of the seedling growth network where the importance of each hub changes over time.en_US
dc.format.mimetypeapplication/pdfen_US
dc.language.isoen_USen_US
dc.rightsCopyright is held by the individual authors.en_US
dc.subjectArabidopsis; Development; Growth; Hormones; Networks; Photomorphogenesisen_US
dc.subject.otherBiologyen_US
dc.subject.otherPlant biologyen_US
dc.subject.otherMolecular biologyen_US
dc.subject.otherbiologyen_US
dc.titleThe what, when & how of seedling growth regulation.en_US
dc.typeThesisen_US
dc.embargo.termsNo embargoen_US


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