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dc.contributor.advisorParichy, David Men_US
dc.contributor.authorMcCann, Anna Elizabethen_US
dc.date.accessioned2014-04-30T16:17:47Z
dc.date.available2014-04-30T16:17:47Z
dc.date.issued2014-04-30
dc.date.submitted2014en_US
dc.identifier.otherMcCann_washington_0250O_12898.pdfen_US
dc.identifier.urihttp://hdl.handle.net/1773/25339
dc.descriptionThesis (Master's)--University of Washington, 2014en_US
dc.description.abstractPigment patterns are one of the most diverse and visually appealing traits of any animal, playing important behavioral and ecological roles in mate choice, shoaling and predator avoidance. In the zebrafish, <italic>Danio rerio</italic>, these patterns result from the organization of neural crest derived pigment cells, offering an opportunity to study mechanisms of fate specification and pattern formation. While recent studies in <italic>D. rerio</italic> examine interactions between black melanophores, yellow xanthophores, and iridescent iridophores during adult pattern formation, little is known about the development of the individual pigment cell lineages, particularly yellow xanthophores. Here, I found that embryonic xanthophores de-differentiate at the start of pigment pattern metamorphosis, yet persist into the adult where some redifferentiate as xanthophores and others remain in an undifferentiated state. The undifferentiated cells that remain are competent to differentiate as xanthophores, but not melanophores, suggesting these cells are fate restricted to the xanthophore lineage. My results identify at least one origin of adult xanthophores in the zebrafish thus contributing to the overall picture of pigment cell development, and more broadly, lending novel insight to neural crest lineage diversification.en_US
dc.format.mimetypeapplication/pdfen_US
dc.language.isoen_USen_US
dc.rightsCopyright is held by the individual authors.en_US
dc.subject.otherBiologyen_US
dc.subject.otherDevelopmental biologyen_US
dc.subject.otherbiologyen_US
dc.titleEmbryonic xanthophore fate in the zebrafish, Danio rerioen_US
dc.typeThesisen_US
dc.embargo.termsNo embargoen_US


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