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Improving qPCR telomere length assays: Controlling for well position effects increases statistical power
(American Journal of Human Biology, 2015-01)
Objectives: Telomere length (TL) is commonly measured using quantitative PCR (qPCR). Although easier than the southern blot of terminal restriction fragments (TRF) TL measurement method, one drawback of qPCR is that it introduces greater measurement error and thus reduces the statistical power of analyses. To address a potential ...