Browsing Faculty and Researcher Data and Papers by Author "McLean, Derek J."
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Germ cell transplantation and the study of testicular function
Russell, Lonnie D.; Griswold, Michael D.; McLean, Derek J.; Johnston, Daniel S. (Elsevier, 2001-01)Spermatogonial stem cell transplantation is a novel technique in which donor testicular cells are transferred into recipient testes. A population of germ cells from a transgenic or mutant donor is introduced ... -
Plzf is required in adult male germ cells for stem cell self-renewal
McLean, Derek J.; de Rooij, Dirk G.; Sharma, Manju; Braun, Robert E.; Griswold, Michael D.; Morris, Jamie L.; Buass, F. William; Kirsh, Andrew L. (Nature Publishing Group, 2004-06)Adult germline stem cells are capable of self-renewal, tissue regeneration and production of large numbers of differentiated progeny. We show here that the classical mouse mutant luxoid affects adult germline ...