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    Acyline: the first study in humans of a potent, new gonadotropin-releasing hormone antagonist 

    Bremner, William J.; Amory, John K.; Herbst, Karen L.; Anawalt, Bradley D. (Endocrine Society, 2002-07)
    Acyline is a novel GnRH antagonist found in animal studies to be a potent suppressor of circulating gonadotropin and testosterone (T) levels. We conducted the first study of acyline administration to humans. Eight healthy, eugonadal young men were administered a series of acyline injections (0, ...
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    Low dose of cyproterone acetate and testosterone enanthate for contraception in men 

    Di Cintio, Giulio; Costantino, Antonietta; Flamigni, Carlo; Meriggiola, M. Cristina; Bremner, William J. (Oxford University Press, 1998-05)
    After a control phase, 10 normal men received cyproterone acetate (CPA) at a dose of 25 mg/day (CPA-25; n=5) or 12.5 mg/day (CPA-12.5; n=5) plus testosterone enanthate (TE) 100 mg/week, for 16 weeks. Throughout the study sperm counts were performed every 2 weeks, and luteinizing hormone (LH), ...

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    AuthorBremner, William J. (2)Amory, John K. (1)Anawalt, Bradley D. (1)Costantino, Antonietta (1)Di Cintio, Giulio (1)Flamigni, Carlo (1)Herbst, Karen L. (1)Meriggiola, M. Cristina (1)Subject5-alpha reductase inhibitors (2)
    Adult (2)
    andrology (2)
    gonadotropins (2)
    Humans (2)Male (2)male contraception (2)
    Safety (2)
    testosterone (2)
    colchicine (1)... View MoreDate Issued2002 (1)1998 (1)

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