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dc.contributor.advisorLin, Lih Y
dc.contributor.authorJing, Peifeng
dc.date.accessioned2017-10-26T20:49:22Z
dc.date.submitted2017-08
dc.identifier.otherJing_washington_0250E_17914.pdf
dc.identifier.urihttp://hdl.handle.net/1773/40550
dc.descriptionThesis (Ph.D.)--University of Washington, 2017-08
dc.description.abstractOptical Tweezers is a valuable and versatile tool in the non-invasive manipulation of micro- and nano-sized particles for biology studies and nanotechnologies. In this dissertation, we propose and demonstrate a two-dimensional photonic crystal enhanced optical tweezers for particles and biological cells with higher trapping efficiency and less photodamage or heat generation. The capabilities of this enhanced optical tweezers include trapping, transporting and patterning latex beads and cells. The trapping efficiency is significantly improved based on the higher gradient of laser intensity distribution. This technology relaxes the requirement on input optical power without additional heat generation, which extends the viability of living cells in the trap. Moreover, we developed a flexible platform using parylene-C integrated with photonic crystal enhanced optical tweezers. This system is utilized for colonizing patterned cells with optimized oxygen plasma treated parylene-C film, as well as measuring the cellular repulsive force between a pair of single cells.
dc.format.mimetypeapplication/pdf
dc.language.isoen_US
dc.rightsCC BY
dc.subjectcellular biology
dc.subjectoptical tweezers
dc.subjectphotonic crystal
dc.subjectOptics
dc.subjectElectrical engineering
dc.subjectCellular biology
dc.subject.otherElectrical engineering
dc.titlePhotonic Crystal Optical Tweezers for Live Biological Samples
dc.typeThesis
dc.embargo.termsRestrict to UW for 1 year -- then make Open Access
dc.embargo.lift2018-10-26T20:49:22Z


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