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Browsing Center for Research in Reproduction and Contraception by Title
Now showing items 114-133 of 220
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Low-dose human chorionic gonadotropin maintains intratesticular testosterone in normal men with testosterone-induced gonadotropin suppression
(Endocrine Society, 2005-05)In previous studies of testicular biopsy tissue from healthy men, intratesticular testosterone (ITT) has been shown to be much higher than serum testosterone (T), suggesting that high ITT is needed relative ... -
A lower dosage levonorgestrel and testosterone combination effectively suppresses spermatogenesis and circulating gonadotropin levels with fewer metabolic effects than higher dosage combinations
(American Society of Andrology, 1999-05)Studies using exogenous high-dosage testosterone (T) or a combination regimen of physiologic T plus high-dosage levonorgestrel (LNG) administration in normal men have shown that oligoazoospermia (<3 ... -
Luteal phase defect: the sensitivity and specificity of diagnostic methods in common clinical use [see comments]
(Elsevier, 1994-07)OBJECTIVE: To assess the sensitivity and specificity of common clinical tests used for the diagnosis of luteal phase defect (LPD). DESIGN: The sensitivity and specificity of these tests for predicting low ... -
Luteal phase deficiency: abnormal gonadotropin and progesterone secretion patterns
(Endocrine Society, 1989-10)Luteal phase deficiency (LPD) is a reproductive disorder associated with infertility and spontaneous abortion. This study was undertaken to determine whether LPD might be related to an abnormal pattern of ... -
Luteal phase deficiency: characterization of reproductive hormones over the menstrual cycle
(Endocrine Society, 1989-10)The recurrent deficiency of progesterone (P) secretion by the corpus luteum has been associated with infertility and habitual abortion and given the clinical diagnosis of luteal phase deficiency (LPD). There ... -
The luteinizing hormone-releasing hormone pulse generator in men: abnormalities and clinical management
(Elsevier, 1990-11)Most men with hypogonadotropic eunuchoidism have absent luteinizing hormone and presumably absent luteinizing hormone-releasing hormone pulses. Pulsatile luteinizing hormone-releasing hormone therapy is ... -
Male Contraception
(Ladybrook Publishing, 2003-04) -
Male contraception: views to the 21st century, Bethesda, MD, USA, 9-10 September 1999
(Elsevier, 2000-03)For men who still wish to father children, the contraceptive options currently available are withdrawal and the condom. Although significant progress has been made on hormonal and vaccine-related approaches ... -
The male contraceptive regimen of testosterone and levonorgestrel significantly increases lean mass in healthy young men in 4 weeks, but attenuates a decrease in fat mass induced by testosterone alone
(Endocrine Society, 2003-03)In hypogonadal men, testosterone (T) in replacement dosages is known to increase fat-free mass (lean mass) and decrease fat mass. In young eugonadal men, similar dosages of T increase lean mass, but much higher dosages of ... -
Male hormonal contraception: effects of injections of testosterone undecanoate and depot medroxyprogesterone acetate at eight-week intervals in chinese men
(Endocrine Society, 2004-05)Surveys indicate that one form of acceptable male hormonal contraception would consist of injections given at 2- to 3-month intervals. This report describes a study of depot medroxyprogesterone acetate (DMPA) ... -
Male hormonal contraception: suppression of spermatogenesis by injectable testosterone undecanoate alone or with levonorgestrel implants in chinese men
(American Society of Andrology, 2004-09)Monthly injections of testosterone undecanoate (TU) act as a male contraceptive by reversibly suppressing spermatogenesis to azoospermia or severe oligoazoospermia in 95% of Chinese men. In 5% of Chinese ... -
Mechanisms involved in the homologous down-regulation of transcription of the follicle-stimulating hormone receptor gene in Sertoli cells
(Elsevier, 2001-02-28)The action of follicle-stimulating hormone (FSH) in spermatogenesis is regulated at a fundamental level by controlling the number of competent receptors present at the surface of Sertoli cells. By controlling ... -
Metabolic and behavioral effects of high-dose, exogenous testosterone in healthy men
(Endocrine Society, 1994-08)In addition to their use as replacement therapy for hypogonadal males, androgens, particularly testosterone (T), are being explored as potential hormonal male contraceptive agents, alone or in combination ... -
Modulation of pulsatile gonadotropin secretion by testosterone in man
(Endocrine Society, 1984-04)In experimental animals, primary testicular deficiency leads to increased LH pulse frequency. Pulsatile FSH secretion has not been well characterized in any species. To determine the effect of testosterone ... -
Molecular genetic analysis of mammalian spermatid differentiation
(Endocrine Society, 1995) -
MSY2 and MSY4 bind a conserved sequence in the 3' untranslated region of protamine 1 mRNA in vitro and in vivo
(American Society for Microbiology, 2001-10)Y-box proteins are major constituents of ribonucleoprotein particles (RNPs) which contain translationally silent mRNAs in gametic cells. We have recently shown that a sequence-specific RNA binding activity ... -
Murine germ cells do not require functional androgen receptors to complete spermatogenesis following spermatogonial stem cell transplantation
(Endocrine Society, 2001-06)Murine germ cells do not require functional androgen receptors to complete spermatogenesis following spermatogonial stem cell transplantation. PG - 2405-8 AB - The spermatogonial stem cell transplantation technique ... -
Nocturnal slowing of pulsatile luteinizing hormone secretion in women during the follicular phase of the menstrual cycle
(Endocrine Society, 1985-07)The gonadotropin secretion pattern in normal reproductive age women (n = 5) was evaluated for the presence of a circadian rhythm. The women volunteered for a series of 24-h admissions in different phases of ... -
Norethisterone enanthate plus testosterone undecanoate for male contraception: effects of various injection intervals on spermatogenesis, reproductive hormones, testis, and prostate
(Endocrine Society, 2005-05)The goal of this study was to find the most favorable injection interval of norethisterone enanthate (NETE) plus testosterone undecanoate (TU) in terms of gonadotropin, sperm suppression, and prostatic effects. ... -
Novel male hormonal contraceptive combinations: the hormonal and spermatogenic effects of testosterone and levonorgestrel combined with a 5alpha-reductase inhibitor or gonadotropin-releasing hormone antagonist
(Endocrine Society, 2005-01)We postulated that the addition of a combined types I and II, 5alpha-reductase inhibitor (dutasteride) or long-acting GnRH antagonist (acyline) to combination testosterone plus levonorgestrel treatment may be advantageous ...