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Browsing Center for Research in Reproduction and Contraception by Title
Now showing items 64-83 of 220
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Fanconi anemia complementation group C is required for proliferation of murine primordial germ cells
(Wiley-Liss, 2000-07)Fanconi anemia is a polygenic trait hypothesized to be a DNA damage repair disease. We show that all three Fanconi anemia loci that have been cloned are expressed in the embryonic gonad during the period of ... -
Feedback effects of the testis on pituitary responsiveness to luteinizing hormone-releasing hormone infusions in the ram
(Endocrine Society, 1980-01) -
Follicle-stimulating hormone is required for quantitatively normal inhibin secretion in men
(Endocrine Society, 1988-12)Inhibin is a glycoprotein hormone produced by the testis and ovary which is postulated to be an important regulator of pituitary FSH secretion. Animal data indicate that inhibin is produced by the Sertoli ... -
Follistatin decreases activin-stimulated FSH secretion with no effect on GnRH-stimulated FSH secretion in prepubertal male monkeys
(Endocrine Society, 1994-04)Follistatin is an activin-binding glycoprotein that decreases FSH secretion in vitro and in vivo in rats. The mechanism by which follistatin acts is unclear, but it has been suggested that it may bind ... -
Galanin overexpressing transgenic mice
(Elsevier, 2002-04)Galanin overexpressing transgenic mice (GAL-tg) were generated on two different promoters. Both lines of GAL-tg displayed high levels of galanin in the hippocampus and reduced sensitivity to seizures, as ... -
Galanin-like peptide (GALP) is a target for regulation by leptin in the hypothalamus of the rat
(Endocrine Society, 2000-07)Galanin-like peptide (GALP), which was recently isolated from the porcine hypothalamus, shares sequence homology with galanin and binds with high affinity to galanin receptors. To study the distribution and ... -
Galanin-like peptide as a link in the integration of metabolism and reproduction
(Elsevier, 2004-07)The arcuate nucleus is a hypothalamic center that couples energetics and reproduction. Peptide-releasing neurons in the arcuate nucleus receive and process humoral signals from the periphery and relay this ... -
Galanin-like peptide as a possible link between metabolism and reproduction in the macaque
(Endocrine Society, 2004-04)Galanin-like peptide (GALP) is a hypothalamic neuropeptide that has been implicated in the control of feeding, metabolism, and reproduction. The goal of this study was to examine the effects of central infusions ... -
The gene encoding PRBP, the mouse homolog of human TRBP, maps to distal chromosome 15
(Springer-Verlag, 1998-05) -
Genetically haploid spermatids are phenotypically diploid
(Nature Publishing Group, 1989-01-26)Because chromosomal homologues segregate from one another during meiosis, spermatids are genetically different. Post-meiotic gene expression could lead to gametic differences, some of which might lead to ... -
George Washington's infertility: why was the father of our country never a father?
(Elsevier, 2004-03)George Washington was the single most important figure in the founding of the United States of America. Numerous biographies of Washington have been written and his name is honored in countless ways, including as the name ... -
Germ cell defects and hematopoietic hypersensitivity to gamma-interferon in mice with a targeted disruption of the Fanconi anemia C gene
(American Society of Hematology, 1996-07-01)Fanconi anemia (FA) is an autosomal recessive chromosome instability syndrome characterized by progressive bone marrow (BM) failure, skeletal defects, and increased susceptibility to malignancy. FA cells are ... -
Germ cell transplantation and the study of testicular function
(Elsevier, 2001-01)Spermatogonial stem cell transplantation is a novel technique in which donor testicular cells are transferred into recipient testes. A population of germ cells from a transgenic or mutant donor is introduced ... -
Germ cell-specific proteins interact with the 3' untranslated regions of Prm-1 and Prm-2 mRNA
(Elsevier, 1994-12)The testis-specific mouse protamine genes (Prm-1 and Prm-2) are transcribed in haploid round spermatids, their mRNAs stored as cytoplasmic ribonucleoprotein particles and translated about 1 week later in ... -
The gonadotropin secretion pattern in normal women of advanced reproductive age in relation to the monotropic FSH rise
(Elsevier, 1996-01)OBJECTIVE: Women of advanced reproductive age are known to demonstrate subtle FSH elevations (monotropic FSH rise) while still retaining ovulatory function. The purpose of this study was to investigate the ... -
Gonadotropin-releasing hormone antagonist plus testosterone: a potential male contraceptive
(Endocrine Society, 1991-09)No effective hormonal contraceptive has yet been devised for men. Through their suppressive effect on gonadotropin secretion, GnRH antagonists inhibit both testosterone (T) production and spermatogenesis in ... -
Gonadotropin-releasing hormone antagonists
(Elsevier, 2003-12)Hypothalamic gonadotropin-releasing hormone (GnRH) is a decapeptide that stimulates pituitary synthesis and secretion of gonadotropins and, therefore, gonadal hormones. GnRH antagonists, of which thousands ... -
Gonadotropin-releasing hormone messenger ribonucleic acid levels are unaltered with changes in the gonadal hormone milieu of the adult male rat
(Endocrine Society, 1990-08)Testicular function is regulated by the negative feedback effect of sex hormones acting at the brain and pituitary to inhibit the secretion of LH and FSH. An important component of this feedback axis is ... -
Gonadotropin-releasing hormone-induced changes in testosterone secretion in normal women
(Elsevier, 1987-09)This study investigated the pattern of testosterone (T) secretion in spontaneous (n = 14) and gonadotropin-releasing hormone (GnRH)-treated (n = 6) menstrual cycles in normal women. In spontaneous cycles, T ... -
Growth hormone receptor messenger ribonucleic acid distribution in the adult male rat brain and its colocalization in hypothalamic somatostatin neurons
(Endocrine Society, 1992-08)The activity of both somatostatin (SS) and GH-releasing hormone (GHRH) neurons within several hypothalamic nuclei is regulated, in part, by the feedback effects of GH. However, whether GH, or its intermediate, ...