Browsing Center for Research in Reproduction and Contraception by Subject "Estrus, drug effects"

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    • Leptin is a metabolic gate for the onset of puberty in the female rat 

      Weigle, David S.; Kuijper, Joseph L.; Steiner, Robert A.; Clifton, Donald K.; Cheung, Clement C.; Thornton, Janice E. (Endocrine Society, 1997-02)
      The timing of puberty onset in mammals is tightly coupled to the animal's nutritional and metabolic state. We conducted two experiments to test the hypothesis that leptin acts as a metabolic signal for the ...