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The association of D-group chromosomal translocations and defective spermatogenesis

Show simple item record Paulsen, C. Alvin en_US Plymate, Stephen R. en_US Bremner, William J. en_US 2008-10-17T20:41:28Z 2008-10-17T20:41:28Z 1976-02 en_US
dc.identifier.citation Fertil Steril. 1976 Feb;27(2):139-44 en_US
dc.description.abstract D-group chromosome translocations have been associated in isolated cases with infertility in males. In this study, we demonstrated the effect of a translocated D-group chromosome on spermatogenesis as it had segregated among three male members of one family. Although the father, who carried the translocation, was obviously fertile, the effects of the translocations on his sperm were noted in the morphologic examination. This study demonstrates the need for more careful evaluation of patients with chromosomal abnormalities for effects on spermatogenesis. Furthermore, it shows the possibility of autosomal chromosomal influences on testicular function en_US
dc.language.iso en_US en_US
dc.publisher Elsevier en_US
dc.subject andrology en_US
dc.subject 5-alpha reductase inhibitors en_US
dc.subject gonadotropins en_US
dc.subject testosterone en_US
dc.subject male contraception en_US
dc.subject.mesh Semen, cytology en_US
dc.subject.mesh Research Support, U.S. Gov't, P.H.S. en_US
dc.subject.mesh Spermatozoa, cytology en_US
dc.subject.mesh Spermatogenesis en_US
dc.subject.mesh Adult en_US
dc.subject.mesh Infertility, Male, genetics en_US
dc.subject.mesh Chromosome Aberrations en_US
dc.subject.mesh Translocation, Genetic en_US
dc.subject.mesh Middle Aged en_US
dc.subject.mesh Oligospermia, complications en_US
dc.subject.mesh Male en_US
dc.subject.mesh Chromosomes, Human, 13-15 en_US
dc.subject.mesh Humans en_US
dc.title The association of D-group chromosomal translocations and defective spermatogenesis en_US
dc.type Article en_US

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