ResearchWorks Archive
    • Login
    View Item 
    •   ResearchWorks Home
    • Faculty and Researcher Data and Papers
    • Research in Reproduction and Contraception, Center for
    • Center for Research in Reproduction and Contraception
    • View Item
    •   ResearchWorks Home
    • Faculty and Researcher Data and Papers
    • Research in Reproduction and Contraception, Center for
    • Center for Research in Reproduction and Contraception
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Abnormal patterns of pulsatile luteinizing hormone in women with luteal phase deficiency

    Thumbnail
    View/Open
    ObstetGynecol_1984_Abnormal_Pattern_Pulsatile.pdf (77.16Kb)
    Date
    1984-05
    Author
    Bremner, William J.
    Clifton, Donald K.
    Soules, Michael R.
    Steiner, Robert A.
    Metadata
    Show full item record
    Abstract
    Luteal phase deficiency is usually a problem of inadequate progesterone production associated with inadequate ovarian follicular development. The hypothesis that luteal phase deficiency results from an abnormal secretion pattern of luteinizing hormone (LH) was tested in these women. To this end, the early follicular LH secretion pattern in four women with luteal phase deficiency was characterized and compared with patterns in normal women. Blood samples were obtained through indwelling catheters every ten minutes for eight hours (10 AM to 6 PM), and plasma levels of LH and FSH were measured. Luteinizing hormone and FSH secretion profiles were analyzed for pulse frequency, amplitude, and mean plasma level. A significantly greater LH pulse frequency in women with luteal phase deficiency was observed when compared with the frequency in normal controls (luteal phase deficiency, 10.5 pulses/eight hours; normal, 5.2 pulses/eight hours; P less than or equal to .05). The mean FSH concentration was less in the women with luteal phase deficiency, but the level was not significant. These data suggest that the abnormal LH secretion pattern observed in women with luteal phase deficiency is responsible for their inadequate luteal phase progesterone secretion and their infertility.
    URI
    http://hdl.handle.net/1773/4363
    Collections
    • Center for Research in Reproduction and Contraception [220]

    DSpace software copyright © 2002-2015  DuraSpace
    Contact Us | Send Feedback
    Theme by 
    @mire NV
     

     

    Browse

    All of ResearchWorksCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects

    My Account

    LoginRegister

    DSpace software copyright © 2002-2015  DuraSpace
    Contact Us | Send Feedback
    Theme by 
    @mire NV