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dc.contributor.authorGriswold, Michael D.en_US
dc.contributor.authorFriel, Patrick J.en_US
dc.contributor.authorJohnston, Daniel S.en_US
dc.contributor.authorRussell, Lonnie D.en_US
dc.date.accessioned2008-10-17T20:43:43Z
dc.date.available2008-10-17T20:43:43Z
dc.date.issued2001-06en_US
dc.identifier.citationEndocrinology. 2001 Jun;142(6):2405-8en_US
dc.identifier.urihttp://hdl.handle.net/1773/4480
dc.description.abstractMurine germ cells do not require functional androgen receptors to complete spermatogenesis following spermatogonial stem cell transplantation. PG - 2405-8 AB - The spermatogonial stem cell transplantation technique was employed to determine if murine germ cells require functional androgen receptors to complete qualitatively normal spermatogenesis. Testicular cells from testicular feminized mice were injected into the seminiferous tubules of azoospermic mice expressing functional androgen receptors. Recipient testes were analyzed between 110 and 200 days following transplantation. Multiple colonies of complete and qualitatively normal donor-derived spermatogenesis were seen within the seminiferous tubules of each recipient testis, demonstrating that murine germ cells do not require functional androgen receptors to complete spermatogenesis.en_US
dc.language.isoen_USen_US
dc.publisherEndocrine Societyen_US
dc.subjectgerm cellen_US
dc.subjectspermatogenesisen_US
dc.subjectstem cellen_US
dc.subjectandrogen receptorsen_US
dc.subject.meshPolymerase Chain Reactionen_US
dc.subject.meshOligospermia, geneticsen_US
dc.subject.meshResearch Support, U.S. Gov't, P.H.S.en_US
dc.subject.meshSpermatogenesisen_US
dc.subject.meshReceptors, Androgen, genetics, physiologyen_US
dc.subject.meshAnimalsen_US
dc.subject.meshMaleen_US
dc.subject.meshTestis, cytologyen_US
dc.subject.meshSpermatogonia, transplantationen_US
dc.subject.meshSpermatozoa, physiology, ultrastructureen_US
dc.subject.meshCell Differentiationen_US
dc.subject.meshSeminiferous Tubules, cytologyen_US
dc.subject.meshMice, Inbred C57BLen_US
dc.subject.meshMutationen_US
dc.subject.meshMiceen_US
dc.subject.meshStem Cell Transplantationen_US
dc.subject.meshFemaleen_US
dc.subject.meshGene Deletionen_US
dc.titleMurine germ cells do not require functional androgen receptors to complete spermatogenesis following spermatogonial stem cell transplantationen_US
dc.typeArticleen_US


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