Browsing Dissertations and Theses by Title
Now showing items 3570-3589 of 16476
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Design of a Pneumatic Tool for Manual Drilling Operations in Confined Spaces
This master’s thesis describes the design process and testing results for a pneumatically actuated, manually-operated tool for confined space drilling operations. The purpose of this device is to back-drill pilot holes ... -
Design of a Rail Gun System for Mitigating Disruptions in Fusion Reactors
Magnetic fusion devices, such as the tokamak, that carry a large amount of current to generate the plasma confining magnetic fields have the potential to lose magnetic stability control. This can lead to a major plasma ... -
Design of a Small-Scale Mixing Section for a Supercritical Water Reactor through the Finite Volume Method
Supercritical water (sc-H2O) reactors have been used for biomass gasification and the destruction of hazardous waste. Laboratory scale reactors are typically used for development of chemical kinetic rate parameters. These ... -
Design of Biomimetic Armor Based on Strain Rate Sensitive Natural Dermal Armor
Elasmoid fish scales serve as a dermal armor and are a marvelous example of a biological composite in Nature that exhibits exceptional mechanical behavior. Their hierarchical microstructure consists of two distinct and ... -
Design of computational imaging systems using wavefront-coded dielectric metasurfaces
High-quality cameras are widely accessible today owing to the ubiquity of smartphones and the miniaturization of sensors driven by improvements in manufacturing. These cameras, however, still rely on assemblies of ... -
Design of De Novo Mimetic Protein of Interleukin-21 and Its Therapeutic Efficacy in Cancer
Interleukin-21 (IL-21) is crucial in coordinating immune cells and has pleiotropic effects in their immune responses. It has established clinical anti-tumor activity for melanoma, non-Hodgkin’s lymphoma, and renal cell ... -
Design of De Novo Mini Fluorescence Activating Proteins as pH and Calcium Biosensors
Recent advances in de novo protein design have enabled the design of mini fluorescence activating proteins (mFAPs): mini β-barrel topologies that bind and stabilize the fluorescent cis-planar state of the fluorogenic ... -
Design of flexible puncture resistant gloves inspired by natural dermal armors
For the purpose of providing protection against potential environmental and physical threats, many animal species have developed hierarchical and heterogeneous biological materials. In turn, scientists and engineers have ... -
Design of gRNA Expression Systems and Characterization of CRISPR Transcriptional Networks in Saccharomyces cerevisiae
The incredibly complex, nuanced, and robust processes happening within cells allow them to adapt to their environment, proliferate, and communicate with their neighbors. These processes are mediated by a network of ... -
Design of Limb Cooling Tourniquet to Prevent Amputation due to Ischemia
During a medevac response, tourniquets are often used as an effective device to mitigate blood loss in incidents involving serious injuries with bleeding. In emergent situations, often involving the transportation of the ... -
Design of multifunctional nanomaterials to improve cancer gene therapy
Gene therapy shows promise for individualized cancer therapies. Compared to conventional treatments, this approach offers a variety of advantages, including a multiplicity of gene targets that define tumor clinical behavior, ... -
Design of Novel Antigens and Immunogens to Improve Influenza Vaccines
Vaccinology has recently been heavily influenced by advances in structural biology that allow for detailed pathogenic insights, antibody characterization, and the redesign of antigens. Outside of vaccinology, advances in ... -
Design of Novel Repeat Proteins Containing Beta Strands
Repeat protein design is a natural direction for protein bioengineering thanks to inherent adaptability, geometric properties, and facile extensibility. Natural systems use repeat proteins as materials scaffolds, sensors, ... -
Design of the DSSL Testbench Hardware Architecture for Rapid Development and Execution of Hardware-in-the-Loop Control
(2013-02-25)This thesis discusses the development of the MATLAB-based Distributed Space Systems Lab (DSSL) Hardware Architecture (or DHA), a software stack and design methodology to allow for rapid hardware and software development ... -
Design of thermoelectric (TE) modules based on TE materials of higher specific figure-of-merit and low-cost materials
(2013-11-14)The efficiency of thermoelectric (TE) materials is determined by the dimensionless figure-of-merit (ZT) defined as ZT = S<super>2</super>σT/κ where, S, σ, κ, and T are Seebeck coefficient, electrical conductivity, thermal ... -
Design Optimization of Structures with Shape Memory Alloy Member Actuators
(2014-02-24)A capability was developed to build a perform mass-minimization of a truss with SMA actuation to determine optimal element diameters and actuator applied temperature changes. The Nonlinear Programming/Approximation Concepts ... -
Design principles for cadmium chalcogenide nanoparticle assembly via peptoids
Self-assembled organic nanomaterials can be generated by bottom-up assembly pathways where the structure is controlled by the organic sequence and altered using pH, temperature, and solvation. These nanomaterials have been ... -
Design recommendations for Pharmacogenomics Clinical Decision Support Systems
The use of pharmacogenomics (PGx)in clinical practice is still facing several challenges in reaching full adoption. PGx is an emerging field that aims to deploy genetic information to target drug therapy. To incorporate ... -
Design Summary : Schematic Design for InterImCDA's Farm & Nature Center Project
(2013-11-14)This report is both a pre-design summary, and site-specific design/build and planning resource, for InterImCDA and their new Farm & Nature Center in the Danny Woo Community Garden, within Seattle's International District. ... -
Design with Diploria: Coral Infrastructure for a New Coastal Future
The growing stressors of global climate change and urbanization have brought about the decline of one of our planet’s most critical biomes - coral reefs. As coral reefs vanish, we lose not only their surrounding ecologies ...