Browsing Dissertations and Theses by Title
Now showing items 5516-5535 of 16476
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Evolution of antiviral breadth in Mx GTPases
As obligate parasites, viral pathogens coopt host resources and subvert cellular processes to promote their own replication. In response, host organisms have evolved numerous countermeasures to thwart viral infection. ... -
Evolution of Aquatic Plants in Rivers and Wetlands across the Andes in northern South America
Northern South America is one of the most biodiverse regions on earth and understanding the causes and processes that have led to the assembly of this rich biota has been central to ecological and evolutionary investigations ... -
Evolution of Endothelin Signaling and Diversification of Adult Pigment Patterns
Vertebrate forms are tremendously diverse. While there are many studies identifying genetic loci that have played a role in diversification, there are fewer that elucidate specific evolutionary changes and mechanisms at ... -
Evolution of Local Coordination of Zn Ions in Aqueous Electrolytes: Chemical, Thermal and Confinement Effects
The accelerating global transition towards renewable energy sources necessitates innovative and sustainable energy storage solutions to effectively manage the intermittent nature of renewable power generation. A key facet ... -
Evolution of Protein Kinase R Antagonism in Primate Cytomegaloviruses
During millions of years of coevolution with their hosts, cytomegaloviruses (CMVs) have succeeded in adapting to overcome host-specific immune defenses, including the protein kinase R (PKR) pathway. Consequently, these ... -
Evolution of Secondary Organic Aerosol Composition, Volatility, and Absorption During Oxidation of Phenolic Compounds Under Conditions Relevant to Biomass Burning
Phenolic compounds emitted from wildfires and biomass burning (BB) are highly reactive and yield secondary organic aerosol (SOA) and brown carbon (BrC) upon oxidation initiated by the hydroxyl radical (OH) and nitrate ... -
Evolution of soft-shell clam transmissible cancer
Transmissible cancers are infectious parasitic clones that metastasize to new hosts, living past the death of the founder animal in which the cancer initiated. Using genomic and transcriptomic analyses, we investigated the ... -
Evolution of Synthetic Nucleocapsids Encapsulating their own RNA genome
Viruses are the simplest example of a fundamental feature of biology— they maintain genotype phenotype linkage in complex biochemical environments by encapsulating and protecting a nucleic acid genome. This allows evolution ... -
The Evolution of Temporal Polyethism
(2013-02-25)Temporal polyethism is a method of division of labor exhibited by many eusocial insect colonies, where the type of task an individual attempts is correlated with its age. The evolutionary pressures that give rise to this ... -
Evolution of the cross-equatorial atmospheric boundary layer in the east Pacific: observations and models
(2004)The NCAR C-130 research aircraft flew eight missions observing the atmospheric boundary layer (ABL) along 95°W, 1°S--12°N. The positive air-sea temperature difference over the equatorial cold tongue results in a shallow ... -
Evolution of the rbcS gene family in Solanaceae: concerted evolution and gain and loss of introns, with a description of new statistical guidelines for determining the number of unique gene copies.
Concerted evolution is a pattern of gene evolution resulting from mechanisms that homogenize gene copies within a lineage. Two mechanisms have been identified that may homogenize <italic>rbcS</italic> copies within Solanaceae. ... -
Evolution-guided design of super restrictor antiviral proteins
Host-virus evolutionary arms-races are driven by antagonistic interactions and often manifest as recurrent amino acid changes (i.e., positive selection) at their protein-protein interaction interfaces. Here, we investigated ... -
Evolutionary adaptations in developmental signaling pathways underlie regenerative scar-free wound repair in African Spiny Mouse (Genus Acomys)
Vertebrate tissue regeneration is a property restricted to a small number of species within the teleost and urodele clades. Contrary to these assumptions, however, all mammalian species examined are also capable of ... -
Evolutionary analysis of viral sequences in eukaryotic genomes
The focus of this work is several evolutionary analyses of endogenous viral sequences in eukaryotic genomes. Endogenous viral sequences can provide key insights into the past forms and evolutionary history of viruses, as ... -
Evolutionary and spatial dynamics underlying intra-tumor heterogeneity
Intra-tumor heterogeneity (ITH) is a pervasive feature of solid tumors that complicates clinical prognosis and management. Yet, the evolutionary processes that explain ITH remain largely unresolved. Here, we demonstrate ... -
Evolutionary Consequences of Metabolic Competition and Cooperation in Microbial Communities
Microbial communities are ubiquitous and perform functions fundamental to life on earth. The high density of organisms within them and the many ways in which these species interact with each other result in limitless ... -
Evolutionary dynamics of influenza virus across spatiotemporal scales
RNA viruses like influenza mutate rapidly to form genetically diverse populations. Recent high-throughput deep sequencing techniques make it possible to track influenza’s evolutionary dynamics at high resolution, showing ... -
Evolutionary Dynamics of Pine Squirrels (Tamiasciurus) in Western North America
(2013-07-25)The evolution of new phenotypes and species is a population genetic process that is governed by four fundamental forces: natural selection, drift, mutation, and gene flow. Ecological genetics is the reciprocal interaction ... -
Evolutionary dynamics under various modes of reproduction
Chapter 1. Dispersal and migration are spatially limited in many natural populations. Such limitations can lead to clustering of like types, which weakens competition between unlike types; thus, the rate by which a fitter ... -
Evolutionary History of the Patagonian Liolaemus fitzingerii Species Group of Lizards
The majority of the world’s land mass and biota reside in the Northern Hemisphere. However, even when land area is accounted for, we know disproportionately less about Southern Hemisphere flora and fauna than their Northern ...