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Browsing Dissertations and Theses by Subject "Pyroptosis"
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Diabetes Exacerbates Atherosclerosis via Inflammasome- and APOC3-Dependent Pathways
Individuals with diabetes suffer from increased cardiovascular disease (CVD) death regardless of statin treatment. The persistently elevated CVD risk among individuals with diabetes suggests the presence of diabetes-associated ... -
Mechanisms of negative regulation of inflammasome activation
Pyroptosis is an inflammatory program of cell death that is coordinated by the assembly of macromolecular structures known as inflammasomes. Pathogenic Yersinia species have evolved specific mechanisms to inhibit inflammasome ... -
The Relationship Between Neurosteroid Structures and Inhibition of Pyroptotic Lysis
Pyroptosis is a form of programmed cell death with inflammatory biologicalconsequences. In moderation, pyroptosis helps to regulate and maintain a healthy immune response in the presence of invading pathogens. However, ...