Browsing Biological chemistry by Title
Now showing items 116-122 of 122
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Undergraduate Research Reports 1 and 2
(1965-11-03)Ferredoxin, a low molecular weight electron transport protein, is found in plants and numerous anaerobic bacteria (6, 17). It was first isolated from Colstridium pasteurianum by Morten et al (23). Ferredoxins from various ... -
Understanding and Manipulating Anti-HIV Antibody Responses via Structural Methods
(2014-02-24)Anti-HIV antibody responses offer one of very few potential routes towards a protective HIV vaccine; structural biochemistry methods such as crystallography and computational modeling can provide key insights for the design ... -
Understanding cardiac metabolism through elucidation of mitochondrial protein-protein interactions
Cardiovascular disease is the leading cause of death worldwide, yet developments of new treatment has been stalled for nearly three decades and novel concepts and strategies are urgently needed. Mitochondria play a central ... -
Understanding coronavirus fusion through structure
Two recent coronavirus epidemics highlight the need for vaccine development since no therapeutic currently exists. There are six known human-infecting coronaviruses and many others that can infect livestock and household ... -
Understanding Protein Folding through Computational Design and Experimental Validation of First Ever De novo All Beta-Sheet Proteins for Plant Biotechnology Applications
β-sheet proteins carry out critical functions in biology, and hence are attractive scaffolds for computational protein design. Through study of loops connecting unpaired β-strands (β-arches), we have identified a series ... -
Using biophysical analysis to study the regulation of the budding yeast kinetochore
Kinetochores are large macromolecular machines that serve to physically segregate the genomic material of a cell during mitosis. To achieve this, the kinetochore must make strong attachments to dynamic microtubules under ... -
Viral proteins as targets for antibody therapeutics and molecular detection agents
The most recent viral pandemic, COVID-19 caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), which has so far resulted in the deaths of 5 million people, is a solemn reminder of the immense burden and ...