Browsing Biological chemistry by Subject "Biology"
Now showing items 1-4 of 4
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Autophagy, or not to be: The delicate balance of cellular self-digestion in neurons and neurodegeneration
(2013-04-17)Neurons rely on autophagy for some critical functions, perhaps even more so than non-neuronal cells [4], but the process does not have such a clear-cut role in these cells. In some cases, autophagy can assist the cell by ... -
Microtubule attachment and regulation mechanisms of the budding yeast kinetochore
Strong kinetochore-microtubule attachments are essential for faithful segregation of sister chromatids during mitosis. The Dam1 and Ndc80 complexes are the main microtubule binding components of the budding yeast kinetochore. ... -
The conserved coiled-coil protein CCCP1 and the endosomal complex EARP regulate dense-core vesicle cargo sorting
The regulated release of peptide hormones (e.g. insulin), neuropeptides, and monoamines depends on their being packaged into dense-core vesicles (DCVs). How these vesicles are made and how their cargo is properly selected ... -
The Role of Microtubule-Associated Proteins During Microtubule Nucleation and Organization
Successful mitotic division is fundamental to life. During mitosis, the cytoskeletal network is reorganized to form the bipolar spindle: microtubules extend from microtubule-organizing centers to attach to and separate ...