Now showing items 1-1 of 1
Computational Design of Hyperstable, De Novo Miniproteins Targeting PD-1
Computational protein design has recently advanced to a new era with the de novo design of stable proteins targeting native protein ligands. In this dissertation, I will present the first de novo protein binder with an all beta interface targeting the T cell receptor, programmed cell death protein 1 (PD-1). Expressed on ...