Browsing Biomedical and health informatics by Title
Now showing items 58-77 of 100
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NGSdb: A NGS Data Management and Analysis Platform for Comparative Genomics
As researchers continue to expand the volume of Next Generation Sequencing data, the ability to store and query the data becomes increasingly important. The current approach of using spreadsheets has become too complex and ... -
No Wrong Door: Designing Health Information Technology to Support Interprofessional Collaboration Around Child Development Work
Child development refers to children gaining the skills they need to succeed in life, consisting of abilities in overlapping domains such as speech, motor, social, and cognition. Developmental disabilities are chronic ... -
On Biological Network Visualization: Understanding Challenges, Measuring the Status Quo, and Estimating Saliency of Visual Attributes
Biomedical research increasingly relies on the analysis and visualization of a wide range of collected data. However, for certain research questions, such as those investigating the interconnectedness of biological elements, ... -
Ontology-Based Data Integration of Open Source Electronic Medical Record and Electronic Data Capture Systems
(2014-02-24)In low-resource settings, the prioritization of clinical care funding is often determined by immediate health priorities. As a result, investment directed towards the development of standards for clinical data representation ... -
Ontology-driven pathway data integration
Biological pathways are useful tools for understanding human physiology and disease pathogenesis. Pathway analysis can be used to detect genes and functions associated with complex disease phenotypes. When performing pathway ... -
Open-Source Computerized Patient-Reported Outcomes: Case Studies Illustrating Fifteen Years of Evolution
Over a fifteen year period, Patient Reported Outcomes ("PRO") applications to support over forty clinical and research projects have driven the evolution of an open-source computerized PRO system ("cPRO", http://cprohealth.org). ... -
Patient-Centered Development and Evaluation of a Mobile Wound Tracking Tool
Surgical site infections (SSI) are a common, costly and serious problem following surgery, affecting at least 500,000 people annually. Most infections now occur after hospital discharge, placing the burden of recognizing ... -
Patient-Peer Support to Improve Quality and Safety in the Hospital
Patient safety is a critical and persistent problem impacting health care systems around the world. Despite major financial and technological investments to improve this problem, medical errors remain a leading cause of ... -
Performance evaluation of a natural language processing tool to extract infectious disease problems
(2013-11-14)Use of a complete problem list can benefit patient care, quality improvement initiatives, and research activities. However, it can be time consuming for physicians to enter the correct encoded problem from a standardized ... -
Physician Perspectives on CYP2C19 Pharmacogenomic Active Clinical Decision Support
Actionable pharmacogenomic (PGx) information is growing exponentially with lowering costs of sequencing technologies, yet the best means to disseminate such data to physicians remains unclear. One method involves alerts ... -
Predicting Cancer Outcome with Multispectral Tumor Tissue Images
Tumor tissue slides have been used by clinicians to assess cancer patient’s condition and indicate prognosis. Several recent studies have suggested that distribution of important immunological biomarkers on tumor tissue ... -
Predictive Approaches for Acute Adverse Events in Electronic Health Records
Medical errors have been cited as the third leading cause of death in the United States in 2013. Failure to rescue (FTR) is a subtype of medical errors and refers to the loss of an opportunity to save a patient’s life after ... -
A Proof of Concept Imaging System for Automated Cervical Cancer Screening in Peru
(2013-07-25)Cervical cancer is the second most frequent cancer in women around the world and affects half a million women per year. The World Health Organization (WHO) estimates that 275,000 women die every year, and 80% to 85% of ... -
Qualitative Assessment of Hot Debriefs for Code Teams at Seattle Children’s Hospital
Seattle Children’s Hospital recently implemented ‘hot debriefs’ for code teams that respond to cardiac or respiratory resuscitation code events. Hot debriefs are meetings immediately after the code event where the code ... -
Reconfiguring the Everyday: Understanding, Designing, and Supporting Chronic Illness Management
From taking medications at the right time to emotionally dealing with their symptoms, patients who have a chronic illness must manage many facets of their illness. Today, patients often utilize different types of general-purpose ... -
Reproducibility in human cognitive neuroimaging: a community-driven data sharing framework for provenance information integration and interoperability
Access to primary data and the provenance of derived data are increasingly recognized as an essential aspect of reproducibility in biomedical research. While productive data sharing has become the norm in some biomedical ... -
RNA-seq generates new insights into Leishmania differentiation
Leishmania donovani, an intracellular parasitic trypanosomatid, causes kala-azar, a fatal form of visceral leishmaniasis in humans. Infection occurs through a cycle whereby parasites (promastigote stage) living in the ... -
Secondary Usage of Electronic Health Record Data for Patient-Specific Modeling
Translational research has become an important bridge that moves findings from basic science research to patients' bedside and to the clinical community. Unfortunately, this notion of translational research seems to be ... -
Secondary Use of Electronic Clinical Data: Barriers, Facilitators and a Proposed Solution
(2013-02-25)The increasing adoption of electronic medical records is producing a massive accumulation of routinelly collected electronic clinical data (ECD). This data can be used not only for direct patient care but for secondary ... -
Supporting collaborative clinical trial protocol writing through an annotation design
(2005)Clinical trial protocols are important documents that guide clinical research. Modern protocol development requires collective expertise from a group of Loosely-Coupled protocol writers, who work across distances and time ...