Browsing Chemical engineering by Subject "chemical engineering"
Now showing items 1-20 of 72
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A Comparative Study of Copper Chalcogenide Nanocrystals as Agents for Photothermal Therapy
In recent years, copper sulfide nanocrystals (NCs) have emerged as promising candidates for new photothermal agents due to their strong near-infrared (NIR) light absorption, high photostability, low toxicity, and suitable ... -
Accelerating protein unfolding simulations: Effect of ionic liquids on villin headpiece unfolding time
We demonstrate an approach to accelerate protein unfolding simulation using the metadynamics (MetaD) method, and the new rate calculation method “infrequent metadynamics”. The accelerated simulation time can be 200 ~ 700 ... -
Adsorption Calorimetry for Energy Conversion Technologies: Applications in Organic Photovoltaics, Catalysis, and Atomic Layer Deposition
Fossil fuel combustion accounts for over two-thirds of greenhouse gas emissions worldwide, and as the global population continues to grow, so does our carbon footprint. The root cause of climate change is relatively simple ... -
Adsorption Calorimetry Measurements of the Energetics of Catalytic Intermediates: Empirical Trends and Benchmarks for Theory
(2013-04-17)Catalysts enable chemical reactions to occur with less energy input than would be required without a catalyst, simultaneously increasing the rate and selectivity of a reaction. Thus, catalysts are important industrial ... -
Afffinity tag excision strategies for Car9-tagged proteins
The demand for cheap methods to evaluate and purify of proteins is growing especially in the emerging sectors of the biologics industries and in research laboratories. In accommodating this demand for growth, we explore ... -
Biocompatible zwitterionic polymer chemistries and hydrogels for gene therapy, drug delivery, and regenerative medicine
Zwitterionic polymers have recently gained significant attention as a unique class of biomaterials, with their superhydrophilicity and unrivaled biocompatibility setting them apart from non-ionic and single-charged polymers. ... -
Bioinspired Anti-fouling Coating on Hydrophobic Surfaces
Anti-biofouling is very important in many applications ranging from marine coatings to biomedical devices. The poor bio-compatibility of medical devices with human body causes undesired effects. Therefore, to achieve ... -
Characterization and Degradation of Fatty Acid Methyl Esters and Biodiesel in Artificial Seawater Under UV Exposure Using Raman Spectroscopy
As global concerns over the environmental impact of petroleum fuels increase, alternatives such as biofuels are becoming more prevalent. Most of the world’s commodities are shipped over the oceans by large cargo vessels ... -
Characterization and Modeling of La{1-x}Sr{x}CoO{3-delta} Solid Oxide Fuel Cell Cathodes Using Nonlinear Electrochemical Impedance Techniques
Solid Oxide Fuel Cells (SOFCs) provide a highly efficient means of chemical to electrical energy conversion, and as such they represent a desirable bridge between current heavy reliance on fossil fuel energy and expanded ... -
Chemical Analysis of Cells and Tissues with Time-of-Flight Secondary Ion Mass Spectrometry
(2013-11-14)In this work the chemical analysis of biological cells and tissues with time-of-flight secondary ion mass spectrometry (ToF-SIMS) was explored. ToF-SIMS has the ability to obtain a mass spectrum with submicron spatial ... -
Chemically-Addressable Protein Entrapment in Silica Sol-Gels
Silica-based sol-gel materials as carriers for immobilization of biological species and subsequent controllable release have experienced great examination since past decade. The transparent and robust network possesses ... -
Computational approaches and tools for modeling biomass pyrolysis
Pyrolysis of lignocellulosic biomass is a promising process capable of producing renewable fuels and chemicals that are currently derived from nonrenewable sources. However, industrial pyrolysis processes to make these ... -
Control of endosomal Toll-like receptor (TLR) signaling by nanoparticles and applications in cancer therapy
(2014-04-30)Toll-like receptors (TLRs) play critical roles in the activation of innate and adaptive immune responses. TLRs 3 and 9 are expressed in endosomal and lysosomal compartments and recognize nucleic acids. The activation of ... -
Design, Analysis, and Translation of 3D Hydrodynamic Tweezer Microeddies
(2013-04-17)The drive to understand the behavior and dynamics of single cells and their connection to population-based properties has prompted the microfluidic community to develop diverse micro-trapping array systems. We present ... -
Developing a Simulation Framework for Modeling Biomolecules in Ionic Liquids
First, we describe the development of a protocol to quickly parameterize and validate ionic liquid force fields. Simulations that use these force fields are shown to accurately predict several thermopysical properties of ... -
Developing Multifunctional Surface Chemistry for Plasmonic Biosensing in Complex Media
During the past decades, plasmonic sensors have been explored extensively due to their ultra-sensitivity and emerged as a new generation of analytical tools. Two of the most widely used and studied plasmonic sensors are ... -
Development of a novel carbon fixation pathway enabled by protein engineering
Metabolic engineering in conjunction with computational protein design has the ability to expand the range of possible metabolic pathways. As a demonstration of this utility, a novel one-carbon assimilation pathway, the ... -
Development of Microfluidic Devices For In Situ Investigation of Cells Using Surface-Enhanced Raman Spectroscopy
Surface-enhanced Raman spectroscopy (SERS) has immerged as a power analytical and sensing technique for many applications in biomedical diagnosis, life sciences, food safety, and environment monitoring because of its ... -
Discovery and Development of Synthetic and Natural Biomaterials for Protein Therapeutics and Medical Device Applications
(2013-11-14)Controlling nonspecific protein interactions is important for applications from medical devices to protein therapeutics. The presented work is a compilation of efforts aimed at using zwitterionic (ionic yet charge neutral) ... -
Drug Encapsulated Aerosolized Microspheres as a Biodegradable, Intelligent Glioma Therapy
The grim prognosis for patients diagnosed with malignant gliomas necessitates the development of new therapeutic strategies for localized and sustained drug delivery to combat tumor drug resistance and regrowth. Here we ...