Browsing Chemical engineering by Title
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A Comparative Study of Copper Chalcogenide Nanocrystals as Agents for Photothermal Therapy
In recent years, copper sulfide nanocrystals (NCs) have emerged as promising candidates for new photothermal agents due to their strong near-infrared (NIR) light absorption, high photostability, low toxicity, and suitable ... -
A Generalized Framework for Machine Re-learning of Complex Process and Kinetic Models
Computer modelling is commonly used to simulate complex systems and thus give insight to the problems with lower cost and more efficiently. However, since they usually characterize real system by using complicated mathematical ... -
A High-resolution 3D Printable Porous Biomaterial
Three-dimension (3D) printing is a novel method to fabricate biomaterials with complex shapes and architectures. A porous biomaterial with 40μm pore size has been found to have good performance in reducing the foreign body ... -
A Study of Zwitterionic Polypeptide-Protein Conjugates
Protein therapeutics has been an attractive approach to serve patients. However, the safety and efficacy of these products are limited by their immunogenicity, low circulation time, and instability. Conjugation is one of ... -
Accelerating Peptoid-Surface Simulations: Peptoid Binding on Au(111) and Au(100)
In nature, proteins and peptides are found to have specific binding on inorganic surface, especially on gold surface. However, the main challenge for synthesized proteins and peptides is their poor stability. Thus, sequence ... -
Accelerating protein unfolding simulations: Effect of ionic liquids on villin headpiece unfolding time
We demonstrate an approach to accelerate protein unfolding simulation using the metadynamics (MetaD) method, and the new rate calculation method “infrequent metadynamics”. The accelerated simulation time can be 200 ~ 700 ... -
Adhesion and Interphase Properties of Reinforced Polymeric Composites
Reinforced polymeric composites are an increasingly utilized material with a wide range of applications. Fiber reinforced polymeric composites, in particular, possess impressive mechanical properties at a fraction of the ... -
Adsorption Calorimetry for Energy Conversion Technologies: Applications in Organic Photovoltaics, Catalysis, and Atomic Layer Deposition
Fossil fuel combustion accounts for over two-thirds of greenhouse gas emissions worldwide, and as the global population continues to grow, so does our carbon footprint. The root cause of climate change is relatively simple ... -
Adsorption Calorimetry Measurements of the Energetics of Catalytic Intermediates: Empirical Trends and Benchmarks for Theory
(2013-04-17)Catalysts enable chemical reactions to occur with less energy input than would be required without a catalyst, simultaneously increasing the rate and selectivity of a reaction. Thus, catalysts are important industrial ... -
Afffinity tag excision strategies for Car9-tagged proteins
The demand for cheap methods to evaluate and purify of proteins is growing especially in the emerging sectors of the biologics industries and in research laboratories. In accommodating this demand for growth, we explore ... -
Aggregation of colloidal particles at the air-water interface
(1991)Various investigators have noted that small particles at an interface exhibit a special tendency to aggregate. The most common manifestations of this phenomenon are the formation of an observable surface coagulum and the ... -
An assessment of alkali metal-O2 chemistry: perspectives and prospectives
Alkali metal-O2 batteries (AOB) have emerged as a promising technology for energy storage due to their large discharge capacity compared to technologies such as lithium-ion batteries. In AOBs, the discharge process involves ... -
An Engineering Framework to Quantify Microglial Morphology in Models of Neurodevelopmental Disease
Microglia, the brain’s immune cells, play major roles in responding to injury and disease, supporting neurodevelopment, and maintaining tissue homeostasis. In response to changes in the brain environment, microglia rapidly ... -
Analyzing small molecule inhibition of enzymes: A preliminary machine learning approach towards drug lead generation
This project is designed to create an implementation of quantitative structure-activity relationships (QSAR) models in Python for the prediction of inhibitory action of small-molecule drugs on the enzyme USP1 - an enzyme ... -
Antioxidant-loaded nanoparticles for the treatment of excitotoxicity in neurological disease
In the United States alone, neurological diseases affect tens of millions of people, costing $800 billion annually. In acute neurological injury, a process known as excitotoxicity manifests from energy failure or direct ... -
Approaches for extending insulin catheter longevity
Implantable medical devices serve a wide range of therapeutic purposes; however, they are an alien material in the body and are subject to the effects of the body’s immune reaction—the foreign body response (FBR). For ... -
BiI3: A Lower Toxicity Route to Tandem Solar Cells
Global population is expected to grow by more than 2 billion people by mid-century. This will result in a large increase in electricity demand. However, any efforts in increasing electricity generation must take into account ... -
Biocompatible zwitterionic polymer chemistries and hydrogels for gene therapy, drug delivery, and regenerative medicine
Zwitterionic polymers have recently gained significant attention as a unique class of biomaterials, with their superhydrophilicity and unrivaled biocompatibility setting them apart from non-ionic and single-charged polymers. ... -
Biodegradable polymeric nanoparticles for neuroprotection against neonatal brain injury
Hypoxic-ischemic encephalopathy (HIE) is the leading cause of permanent brain injury in term newborns. HIE can lead to significant impairments during development and adulthood including cerebral palsy, learning disability, ... -
Bioinspired Anti-fouling Coating on Hydrophobic Surfaces
Anti-biofouling is very important in many applications ranging from marine coatings to biomedical devices. The poor bio-compatibility of medical devices with human body causes undesired effects. Therefore, to achieve ...