Browsing Chemistry by Title
Now showing items 90-109 of 463
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Dancing at the Interface: Surface-Mediated Active Site Dynamics within Molecular Nanoclusters
The key to accessing next-generation heterogeneous catalysts, which lie at the heart of many industrial manufacturing and energy conversion processes, is the identification and detailed surveillance of the catalytic active ... -
Deciphering the biochemical crosstalk of histone sumoylation in human chromatin
The histone code hypothesis states that posttranslational modifications (PTMs) of amino acids at the histone protein termini can combinatorially regulate key DNA processes such as replication, repair, and transcription. ... -
Defect-Related Luminescence in Nanocrystals: Spectroscopy and Computation
Dopants and defects play an important role in the luminescence of semiconductors, from classic bulk phosphors to more recently developed colloidal nanocrystals. This thesis describes several studies on the photophysics of ... -
Design and Characterization of Novel Tandem Ion Mobility Mass Spectrometry Instrumentation
Native ion mobility (IM) mass spectrometry (MS) is a gas-phase structural biology technique that couples low-pressure, electrophoretic separation of ions with mass detection to provide low-resolution information on the ... -
Design and Synthesis of New Organic Semiconductors for Organic Solar Cells
Molecular design and synthesis play critical roles in the development of organic semiconductors for organic photovoltaics (OPVs). This dissertation describes the design, synthesis, and characterization of three classes of ... -
Design and Synthesis of Organic Functional Materials for Energy Conversion and Storage Applications
Carbon emission from consumption of fossil fuels has led to global warming accompanying with a large number of environmental issues. In order to lessen the strong dependence on fossil fuels in modern society, it is crucial ... -
Design principles for cadmium chalcogenide nanoparticle assembly via peptoids
Self-assembled organic nanomaterials can be generated by bottom-up assembly pathways where the structure is controlled by the organic sequence and altered using pH, temperature, and solvation. These nanomaterials have been ... -
Design, synthesis, and evaluation of cholera toxin inhibitors and [alpha]-helix mimetics of dormancy survival regulator
(2006)Infectious diseases cause millions of deaths each year. The top single disease killers include tuberculosis (TB) and diarrheal diseases. The diarrheal diseases caused by cholera toxin (CT) and Escherichia coli heat-labile ... -
Designing nickel- and palladium-based precatalysts to improve catalyst-transfer polymerization towards conjugated polymer synthesis
Catalyst transfer polymerization (CTP) is a versatile synthetic tool to obtain access to sequence specific π-conjugated polymers, which are attractive materials for organic electronics. CTP proceeds through a chain-growth ... -
Designing Polymer Hydrogels for Extrusion-Based Additive Manufacturing
Additive manufacturing (AM) technologies are expanding the boundaries of materials science and providing an exciting forum for interdisciplinary research. The ability to fabricate arbitrarily complex objects has made AM ... -
Designing Quantum Dot Interfaces for Photoredox Catalysis
Chemical manufacturing accounts for 10% of total global energy consumption and 7% of greenhouse emissions. Thermodynamically uphill reactions may be driven by photoredox catalysts under ambient conditions, converting solar ... -
Designing the Interface of Transition Metal Phosphides for Electrocatalysis
Colloidally synthesized nanocrystals are a compelling class of materials for catalysis due to their high surface-area-to-volume ratios. The surface chemistry of nanocrystal catalysts is particularly important because of ... -
Detection of Lysosomal Storage Disorders Using Tandem Mass Spectrometry
(2014-04-30)Lysosomal storage disorders is a group of diverse autosomal recessive metabolic diseases. These disorders are caused by a deficiency in an enzyme necessary for the catabolic degradation of proteins, glycolipids, and ... -
Determination of the structure and dynamics of salivary statherin and N-terminal fragments bound to hydroxyapatite using solid state NMR
(2000)This dissertation contains solid-state NMR studies of the structure and dynamics of the biomineralization protein, salivary statherin, adsorbed onto its relevant biomineral surface, hydroxyapatite. The structure of statherin ... -
Developing Analytical Nonlinear Microscopy Techniques to Study Biomedical Systems
Analytical nonlinear microscopy (ANM) is an indispensable tool for quantitative imaging. Specifically, ANM has found significant utility for characterization of dynamic biomedical systems due to its high spatial and temporal ... -
Developing Catalytically Active Living Materials for Additive Manufacturing
Living materials are created through the embedding of live, whole cells into a matrix that can house and sustain the viability of the encapsulated cells. Through the cell immobilization process, their bioactivity (natural ... -
Developing gold- and silver-catalyzed dehydrogenative cross-coupling toward donor-acceptor polymer synthesis
pi-Conjugated polymers are materials of interest for use in organic electronics. Within these polymers, donor-acceptor polymers are favorable for solar cell applications due to improved charge mobility, better absorption ... -
Development and Analysis of Computational Methods to Study Hydrogen Bonding in Molecular Clusters
Understanding the role of hydrogen bonding in the structure and dynamics of water is an ongoing challenge in physical chemistry. In particular, understanding how the quantum mechanical effects of molecular vibrations govern ... -
Development and Application of Improvements to the Tile-based Fisher Ratio Method and Fundamental Instrument Considerations for Non-targeted Analysis using Two-dimensional Gas Chromatography
Comprehensive two-dimensional gas chromatography with time-of-flight mass spectrometry GC×GC–TOFMS has arguably made possible the largest increase in gas chromatograph performance since the innovation of the wall-coated ... -
Development and Application of Novel Methodologies for the Characterization of Phospholipase A2 Activity: Targeted Lipidomic Profiling and Interfacial Binding Analysis
(2013-07-23)Phospholipases A2 are a family of enzymes that hydrolyze membrane glycerophospholipids to yield free fatty acids and lysophospholipids. Both products serve as precursors for an array of lipid mediators that play known roles ...