Browsing Chemistry by Title
Now showing items 185-204 of 463
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Facilitating Realistic and Efficient Applications of Ab Initio Electronic Dynamics for Polyatomic Systems
Tremendously useful insights for the design and development of nano-scale systems, e.g. photovoltaics devices, can be gained from studying molecular process and reactions using \textit{ab initio} electronic dynamics, i.e. ... -
Flow injection methods for drug-receptor interaction studies, based on probing cell metabolism
(1999)The thesis describes the development of methods to study responses of living cells to chemical stimulation. To measure the responses, the developed methods utilize effects that the responses have on the rate of the cells' ... -
Fluorescence-Enabled Electrochemical Microscopy and Nanoscale Electrochemical Analysis
(2013-07-25)This dissertation discusses the fundamental study of several electroanalytical chemistry tools and methods. Unifying factors between the various chapters include the use of nano and microscale materials for electrode ... -
Fluorescent Labeling Methods for Super-resolution and Optical-sectioning Imaging
Throughout the development of light and fluorescence microscopy, a variety of labeling methods have evolved; from mostly affinity-based labeling used in histological staining to specific labeling using antibodies and ... -
From Energy Generation to Storage: The Exploration of Unusual Architectures and Functions of Conjugated Organic Molecules
The advent of conjugated polymers spurred the field of organic electronics. Since the inception of the field, many have lauded the potential benefits of organic over inorganic platforms, including their light weight, ... -
From Geometry Optimization to Time Dependent Molecular Structure Modeling: Method Developments, ab initio Theories and Applications
(2012-09-13)This dissertation consists of two general parts: I. developments of optimization algorithms (both nuclear and electronic degrees of freedom) for time-independent molecules and II. novel methods, first-principle theories ... -
Fundamental and Applied Investigations in Solid-State Polymer Mechanochemistry
The translation of mechanical force to specific chemical reactivity within polymeric materials is known as polymer mechanochemistry. While this phenomenon has long been observed in homopolymers, it has recently attracted ... -
Fundamental Considerations in One and Two-Dimensional Chromatography for Improved Chemometric Analysis
One and two-dimensional chromatography offer well-established instrumental platforms that produce separations of chemical compounds in complex samples in a variety of fields and applications and when coupled with spectral ... -
Fundamental Insights into Catalyst Design: Energetics of Metal Atom Adsorption and Nanoparticle Adhesion on Oxide Surfaces
Heterogeneous catalysts consisting of transition metal nanoparticles dispersed on high surface area oxide supports are ubiquitous in industrial-scale chemistry and alternative energy technology. Despite their importance, ... -
Fundamental studies of Rocket propellant fuel using GC × GC - TOFMS instrumentation with chemometric data analysis
University of Washington Abstract Fundamental studies of Rocket propellant fuel using GC × GC &mdash TOFMS instrumentation with chemometric data analysis. Benjamin Kehimkar Chair of the Supervisory Committee: Professor ... -
Fundamental Studies on Model Catalyst Systems: Energetics of Metal Nanoparticles Supported on Oxide Surfaces and Microkinetic Analysis Using Degree of Rate Control
This dissertation includes the study of metal nanoparticles supported on oxide surfaces and the microkinetic analysis of complex reaction mechanisms using the degree of rate control (DRC). In Chapters 2-5, the energetics, ... -
Fundamentals and Applications of Biological EPR Spectroscopy
This thesis details robust experimental investigations of sample conditions for EPR spectroscopy. This work investigates two areas of sample conditions. First, a robust experimental investigation of the effect of sample ... -
Gaseous Studies of Ionic Chromophores and Peptide Cation Radicals Generated from Electron Transfer
University of Washington Abstract Gaseous Studies of Ionic Chromophores and of Peptide Cation Radicals Generated from Electron Transfer Robert H. Pepin Chair of the Supervisory Committee: Professor František Tureček ... -
Generation and Action Spectroscopy of Gaseous DNA Cation Radicals
Reactions between genetic material and secondary low-energy electrons emitted from high energy radiation can cause various DNA lesions such as base modifications and cleavage, single strand breaks and double strand breaks. ... -
Global Methods for Discovering and Characterizing Regulatory Mechanisms of Multi-Domain Protein Kinase
Perturbations to cellular phosphorylation levels are highly correlated with a variety of disease states. Because protein kinases are the enzymes responsible for protein phosphorylation, they play a central role in maintaining ... -
Gold-Catalyzed Asymmetric Synthesis of Cyclic Ethers and Copper-Catalyzed Hydrofunctionalization of Alkynes
Gold-catalyzed cyclization of enantioenriched trisubstituted allenols to form enantioenriched α-tetrasubstituted cyclic ethers has been developed. This structural motif can be found in many natural products that have useful ... -
Grating light reflection spectroscopy
(1996)A new optical technique for analytical sensing, termed Grating Light Reflection Spectroscopy (GLRS), is described and evaluated in this dissertation. GLRS relies on the existence of thresholds in diffracted transmitted ... -
Guanidine donors in nonlinear optical chromophores
(2006)The variable refractive index of electro-optic (EO) materials has led to a great deal of research interest. Application of an electric field to EO materials leads to a linear variance in refractive index known as Pockel's ... -
Hallmarks of Reversible Phase Separation in Living, Unperturbed Cell Membranes
Controversy has long surrounded the question of whether spontaneous lateral demixing of membranes into coexisting liquid phases can organize proteins and lipids on micron scales within unperturbed, living cells. A clear ... -
Helping Observe and Tune Diffusion Using Mn2+ Photophysics in Inorganic Nanocrystals after Growth
Doped inorganic crystals exhibit attractive optical, electrical, and magnetic properties that enabled the development of important modern technologies including ruby lasers and silicon microelectronics. The next frontier ...